Rimonabant in rats with a metabolic syndrome
Future innovations in anti-platelet therapies
Arsenic trioxide and auranofin inhibit selenoprotein synthesis
Lapaquistat acetate, a squalene synthase inhibitor, changes macrophage/lipid-rich coronary plaques of hypercholesterolaemic rabbits into fibrous lesions
Importance of vagally mediated bradycardia for the induction of torsade de pointes in an in vivo model
Chronic ethanol intake modulates vascular levels of endothelin-1 receptor and enhances the pressor response to endothelin-1 in anaesthetized rats
Endothelial nitric oxide attenuates Na+/Ca2+ exchanger-mediated vasoconstriction in rat aorta
Sites of action of hydrogen peroxide on ion transport across rat distal colon
Cannabidiol, extracted from Cannabis sativa , selectively inhibits inflammatory hypermotility in mice
A cholecystokinin-1 receptor agonist (CCK-8) mediates increased permeability of brain barriers to leptin
Crocetin improves the insulin resistance induced by high-fat diet in rats
Urocortin ameliorates diabetic nephropathy in obese db/db mice
Regulation of M2-type pyruvate kinase mediated by the high-affinity IgE receptors is required for mast cell degranulation
The cannabinoid receptor-1 antagonist rimonabant inhibits platelet activation and reduces pro-inflammatory chemokines and leukocytes in Zucker rats
Rapamycin affects early fracture healing in mice
In vivo pharmacological evaluation of compound 48/80-induced airways oedema by MRI
Involvement of the BLT2 receptor in the itch-associated scratching induced by 12-( S )-lipoxygenase products in ICR mice
Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes
Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice
Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1
Anticonvulsant effect of BmK IT2, a sodium channel-specific neurotoxin, in rat models of epilepsy
Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice
Increased susceptibility of annexin-A1 null mice to nociceptive pain is indicative of a spinal antinociceptive action of annexin-A1
The μ-opioid receptor agonist morphine, but not agonists at δ- or κ-opioid receptors, induces peripheral antinociception mediated by cannabinoid receptors
Brain oxytocin receptors mediate ejaculation elicited by 7-hydroxy-2-(di- N -propylamino) tetralin (7-OH-DPAT) in anaesthetized rats
Pharmacological profile of the clonidine-induced inhibition of vasodepressor sensory outflow in pithed rats
Discovery and biological characterization of a novel series of androgen receptor modulators