2010 Re-launch of BJP
Mandarin Translations
Reducing QT liability and proarrhythmic risk in drug discovery and development
An introduction to QT interval prolongation and non-clinical approaches to assessing and reducing risk
Dealing with hERG liabilities early : diverse approaches to an important goal in drug development
Value of non-clinical cardiac repolarization assays in supporting the discovery and development of safer medicines
Update on the evaluation of a new drug for effects on cardiac repolarization in humans : issues in early drug development
The thorough QT/QTc study 4 years after the implementation of the ICH E14 guidance
Drug-induced QT interval shortening : potential harbinger of proarrhythmia and regulatory perspectives
Facts, fancies and follies of drug-induced QT/QTc interval shortening
Dog left ventricular midmyocardial myocytes for assessment of drug-induced delayed repolarization : short-term variability and proarrhythmic potential
Dexrazoxane protects the heart from acute doxorubicin-induced QT prolongation : a key role for I Ks
Pharmacological and electrophysiological characterization of nine, single nucleotide polymorphisms of the hERG-encoded potassium channel
Integrated risk assessment and predictive value to humans of non-clinical repolarization assays
Antidepressant-like effects of cannabidiol in mice : possible involvement of 5-HT1A receptors
Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist
Transient supersensitivity to α-adrenoceptor agonists, and distinct hyper-reactivity to vasopressin and angiotensin II after denervation of rat tail artery
NS309 restores EDHF-type relaxation in mesenteric small arteries from type 2 diabetic ZDF rats
Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats
Pharmacokinetic–pharmacodynamic modelling of the analgesic effects of lumiracoxib, a selective inhibitor of cyclooxygenase-2, in rats
Mechanisms involved in the regulation of bovine pulmonary vascular tone by the 5-HT1B receptor
Dopamine transporter down-regulation following repeated cocaine : implications for 3,4-methylenedioxymethamphetamine-induced acute effects and long-term neurotoxicity in mice
Arachidonic acid release mediated by OX1 orexin receptors
Differential actions of urocortins on neurons of the myenteric division of the enteric nervous system in guinea pig distal colon
Role of the signal peptide in the synthesis and processing of the glucagon-like peptide-1 receptor