Non–synaptic receptors and transporters involved in brain functions and targets of drug treatment
Current status and new developments in the treatment of psoriasis and psoriatic arthritis with biological agents
The complex G protein–coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets
Compromised vascular endothelial cell SKCa activity : a fundamental aspect of hypertension?
Impairment of endothelial SKCa channels and of downstream hyperpolarizing pathways in mesenteric arteries from spontaneously hypertensive rats
Prostaglandin signalling in cerebral ischaemia
Microsomal prostaglandin E synthase–1 contributes to ischaemic excitotoxicity through prostaglandin E2 EP3 receptors
Mechanisms mediating the ability of caffeine to influence MDMA (‘Ecstasy’)–induced hyperthermia in rats
Transfer of the glycosylphosphatidylinositol–anchored 5′–nucleotidase CD73 from adiposomes into rat adipocytes stimulates lipid synthesis
Quantitative analysis of neuropeptide Y receptor association with β–arrestin2 measured by bimolecular fluorescence complementation
The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone
Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety
A novel quinone–based derivative (DTNQ–Pro) induces apoptotic death via modulation of heat shock protein expression in Caco–2 cells
A monobromobimane–based assay to measure the pharmacokinetic profile of reactive sulphide species in blood
Simultaneous detection of intracellular target and off–target binding of small molecule cancer drugs at nanomolar concentrations
The xanthine derivative KMUP–1 inhibits models of pulmonary artery hypertension via increased NO and cGMP–dependent inhibition of RhoA/Rho kinase
Purinoreceptor–mediated current in myocytes from renal resistance arteries
Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer
ENaC–mediated effects assessed by MRI in a rat model of hypertonic saline–induced lung hydration
Kinetic analysis of novel mono– and multivalent VHH–fragments and their application for molecular imaging of brain tumours