Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration
Principles of early drug discovery
How accurate is in vitro prediction of carcinogenicity?
Improving planning, design, reporting and scientific quality of animal experiments by using the Gold Standard Publication Checklist, in addition to the ARRIVE guidelines
Anti-angiogenic effects of two cystine-knot miniproteins from tomato fruit
Kukoamine B, a novel dual inhibitor of LPS and CpG DNA, is a potential candidate for sepsis treatment
Betulinic acid inhibits endotoxin-stimulated phosphorylation cascade and pro-inflammatory prostaglandin E2 production in human peripheral blood mononuclear cells
Ser352 and Ser354 in the carboxyl terminus of the human P2Y1 receptor are required for agonist-promoted phosphorylation and internalization in MDCK cells
Functional antagonism of β-adrenoceptor subtypes in the catecholamine-induced automatism in rat myocardium
Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABAA receptors in vitro
Pharmacological characterization of the cytoprotective effects of polyunsaturated fatty acids in insulin-secreting BRIN-BD11 cells
Chronic nicotine treatment differentially modifies acute nicotine and alcohol actions on GABAA and glutamate receptors in hippocampal brain slices
The flavonoid baicalein promotes NMDA receptor-dependent long-term potentiation and enhances memory
Protein kinase C regulates the internalization and function of the human organic anion transporting polypeptide 1A2
Sildenafil, a phosphodiesterase type 5 inhibitor, attenuates diabetic nephropathy in non-insulin-dependent Otsuka Long-Evans Tokushima Fatty rats
The antipyretic effect of dipyrone is unrelated to inhibition of PGE2 synthesis in the hypothalamus
Inhibition of inositol monophosphatase by lithium chloride induces selective macrophage apoptosis in atherosclerotic plaques
The C-terminal fragment of parathyroid hormone-related peptide promotes bone formation in diabetic mice with low-turnover osteopaenia
Ligand-induced internalization of the orexin OX1 and cannabinoid CB1 receptors assessed via N-terminal SNAP and CLIP-tagging