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Rescuing iron-overloaded macrophages by conservative relocation of the accumulated metal
hERG subunit composition determines differential drug sensitivity
Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of risperidone in healthy subjects with CYP2D6 * 10 /* 10
Role of TNF-α in virus-induced airway hyperresponsiveness and neuronal M2 muscarinic receptor dysfunction
On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum
Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1 and Y2 receptors
Effects of inhibitors of hydrogen sulphide synthesis on rat colonic motility
The indolocarbazole, Gö6976, inhibits guanylyl cyclase-A and -B
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action
Structural determinants of allosteric antagonism at metabotropic glutamate receptor 2: mechanistic studies with new potent negative allosteric modulators
Adrenoceptor activity of muscarinic toxins identified from mamba venoms
VS-105: a novel vitamin D receptor modulator with cardiovascular protective effects
Antagonism of the antithrombotic and anti-atherosclerotic actions of aspirin by rofecoxib in the cholesterol-fed rabbit
Nitric oxide-donating statin improves multiple functions of circulating angiogenic cells
Natriuretic peptide receptor-3 underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide
Rosuvastatin improves endothelial function in db/db mice: role of angiotensin II type 1 receptors and oxidative stress
Effects of metoprolol therapy on cardiac gap junction remodelling and conduction in human chronic atrial fibrillation
Intrathecal neuromedin U induces biphasic effects on sympathetic vasomotor tone, increases respiratory drive and attenuates sympathetic reflexes in rat
Changes in aldehyde dehydrogenase 2 expression in rat blood vessels during glyceryl trinitrate tolerance development and reversal
Role of LOX/COX pathways in 3-nitropropionic acid-induced Huntington's Disease-like symptoms in rats: protective effect of licofelone
The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys
Hydrophobic anions potently and uncompetitively antagonize GABAA receptor function in the absence of a conventional binding site
Anti-nociceptive effect of kinin B1 and B2 receptor antagonists on peripheral neuropathy induced by paclitaxel in mice
Paeoniflorin suppresses the expression of intercellular adhesion molecule-1 (ICAM-1) in endotoxin-treated human monocytic cells
Agmatine in the hypothalamic paraventricular nucleus stimulates feeding in rats: involvement of neuropeptide Y
Lidocaine reduces the transition to slow inactivation in Nav1.7 voltage-gated sodium channels
Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells
Pharmacological properties of the rhesus macaque monkey P2X7 receptor
Defining protein kinase/phosphatase isoenzymic regulation of mGlu5 receptor-stimulated phospholipase C and Ca2+ responses in astrocytes
Antagonists show GTP-sensitive high-affinity binding to the sigma-1 receptor
2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidin-2-ylthio)octanoic acid (HZ52) – a novel type of 5-lipoxygenase inhibitor with favourable molecular pharmacology and efficacy in vivo
SPA0355, a thiourea analogue, inhibits inflammatory responses and joint destruction in fibroblast-like synoviocytes and mice with collagen-induced arthritis
Reciprocal modulation of anti-IgE induced histamine release from human mast cells by A1 and A2B adenosine receptors
Significant systemic and mucosal immune response induced on oral delivery of diphtheria toxoid using nano-bilosomes
Tadalafil analgesia in experimental arthritis involves suppression of intra-articular TNF release