New updated GRAC Fifth Edition with searchable online version Launch of new portal Guide to Pharmacology in association with NC-IUPHAR Transporter-Themed Issue
Transporters are an under-developed therapeutic target. Discuss
Mammalian peroxisomal ABC transporters: from endogenous substrates to pathology and clinical significance
The ABCG family of membrane-associated transporters: you don't have to be big to be mighty
The emerging physiological roles of the SLC14A family of urea transporters
The SLC23 family of ascorbate transporters: ensuring that you get and keep your daily dose of vitamin C
The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport
Importance of the multidrug and toxin extrusion MATE/SLC47A family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomics
Opioids and the immune system: what is their mechanism of action?
Depletion and recovery of lymphoid subsets following morphine administration
At last, a truly selective EP2 receptor antagonist
In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP2 receptor antagonist
Bile pigment pharmacokinetics and absorption in the rat: therapeutic potential for enteral administration
Contrasting actions of diesel exhaust particles on the pulmonary and cardiovascular systems and the effects of thymoquinone
Cyclopeptide RA-V inhibits angiogenesis by down-regulating ERK1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells
Reduction of body weight, liver steatosis and expression of stearoyl-CoA desaturase 1 by the isoflavone daidzein in diet-induced obesity