Inotropes and vasopressors: more than haemodynamics!
Vasopressors in shock: too early to move away from catecholamines?
Use of inotropes and vasopressor agents in critically ill patients
Cyclosporin variably and inconsistently reduces infarct size in experimental models of reperfused myocardial infarction: a systematic review and meta-analysis
Endogenous migration modulators as parent compounds for the development of novel cardiovascular and anti-inflammatory drugs
Glycine, a simple physiological compound protecting by yet puzzling mechanism(s) against ischaemia–reperfusion injury: current knowledge
Triphasic blood pressure responses to cannabinoids: do we understand the mechanism?
Pharmacological modulation of GITRL/GITR system: therapeutic perspectives
Resolution of leucocyte-mediated mucosal diseases. A novel in vivo paradigm for drug development
Allosteric modulators can restore function in an amino acid neurotransmitter receptor by slightly altering intra-molecular communication pathways
Function of hyperekplexia-causing α1R271Q/L glycine receptors is restored by shifting the affected residue out of the allosteric signalling pathway
Thiocolchicoside a semi-synthetic derivative of the Glory Lily: a new weapon to fight metastatic bone resorption?
Thiocolchicoside suppresses osteoclastogenesis induced by RANKL and cancer cells through inhibition of inflammatory pathways: a new use for an old drug
Low dose of propranolol down-modulates bone resorption by inhibiting inflammation and osteoclast differentiation
The metabolism and pharmacokinetics of phospho-sulindac (OXT-328) and the effect of difluoromethylornithine
Inhibition of voltage-gated Na+ currents in sensory neurones by the sea anemone toxin APETx2
Sulphide quinone reductase contributes to hydrogen sulphide metabolism in murine peripheral tissues but not in the CNS
Vasoconstrictor and vasodilator responses to tryptamine of rat-isolated perfused mesentery: comparison with tyramine and β-phenylethylamine
Development of a radioiodinated apoptosis–inducing ligand, rhTRAIL, and a radiolabelled agonist TRAIL receptor antibody for clinical imaging studies
A novel compound PTIQ protects the nigral dopaminergic neurones in an animal model of Parkinson's disease induced by MPTP
Characteristics of concatemeric GABAA receptors containing α4/δ subunits expressed in Xenopus oocytes
Restoration of ion channel function in deafness-causing KCNQ4 mutants by synthetic channel openers
High potency inhibition of hERG potassium channels by the sodium–calcium exchange inhibitor KB-R7943
Anti-obesity efficacy of LH-21, a cannabinoid CB1 receptor antagonist with poor brain penetration, in diet-induced obese rats
Orexin A in rat rostral ventrolateral medulla is pressor, sympatho-excitatory, increases barosensitivity and attenuates the somato-sympathetic reflex
Molecular pharmacological profile of a novel thiazolinone-based direct and selective 5-lipoxygenase inhibitor
Mechanism of action of a nanomolar potent, allosteric antagonist of the thyroid-stimulating hormone receptor
Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats
Using microdialysis to analyse the passage of monovalent nanobodies through the blood–brain barrier
Transient receptor potential melastatin 4 inhibitor 9-phenanthrol abolishes arrhythmias induced by hypoxia and re-oxygenation in mouse ventricle
Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β2-adrenoceptors and exacerbates lung inflammation in mice
Krüppel-like factor 4 is induced by rapamycin and mediates the anti-proliferative effect of rapamycin in rat carotid arteries after balloon injury
Potassium and ANO1/ TMEM16A chloride channel profiles distinguish atypical and typical smooth muscle cells from interstitial cells in the mouse renal pelvis