Novel cAMP signalling paradigms: therapeutic implications for airway disease
Modulation of T cell immune functions by the prostaglandin E2 – cAMP pathway in chronic inflammatory states
A-kinase anchoring proteins as potential drug targets
Regulation of the inflammatory response of vascular endothelial cells by EPAC1
cAMP and Epac in the regulation of tissue fibrosis
The role of targeted chemical proteomics in pharmacology
A novel GABAA receptor pharmacology: drugs interacting with the α+β- interface
Analgesic conotoxins: block and G protein-coupled receptor modulation of N-type (CaV2.2) calcium channels
HCN channels in the heart: lessons from mouse mutants
The functions of TRPA1 and TRPV1: moving away from sensory nerves
Endothelial actions of atrial and B-type natriuretic peptides
Preclinical studies identify novel targeted pharmacological strategies for treatment of human malignant pleural mesothelioma
Verapamil as an antiarrhythmic agent in congestive heart failure: hopping from rabbit to human?
Blockade of ICa suppresses early afterdepolarizations and reduces transmural dispersion of repolarization in a whole heart model of chronic heart failure
Upping the antedrug: is a novel anti-inflammatory Toll-like receptor 7 agonist also a bronchodilator?
Biological characterization of a novel class of toll-like receptor 7 agonists designed to have reduced systemic activity
Cholesteryl butyrate solid lipid nanoparticles inhibit the adhesion and migration of colon cancer cells
Novel blockers of hyperpolarization-activated current with isoform selectivity in recombinant cells and native tissue
Gallium compound GaQ3-induced Ca2+ signalling triggers p53-dependent and -independent apoptosis in cancer cells
The neuroregenerative mechanism mediated by the Hsp90-binding immunophilin FKBP52 resembles the early steps of neuronal differentiation
3-Iodothyronamine: a modulator of the hypothalamus-pancreas-thyroid axes in mice
The N-terminal region of the dopamine D2 receptor, a rhodopsin-like GPCR, regulates correct integration into the plasma membrane and endocytic routes
β-Adrenergic receptors stimulate interleukin-6 production through Epac-dependent activation of PKCδ/p38 MAPK signalling in neonatal mouse cardiac fibroblasts
The electro-mechanical window in anaesthetized guinea pigs: a new marker in screening for Torsade de Pointes risk
17β-Oestradiol inhibits doxorubicin-induced apoptosis via block of the volume-sensitive Cl- current in rabbit articular chondrocytes
Involvement of α2- and β2-adrenoceptors on breast cancer cell proliferation and tumour growth regulation
A combinatorial in silico and cellular approach to identify a new class of compounds that target VEGFR2 receptor tyrosine kinase activity and angiogenesis
Ethyl pyruvate promotes spinal cord repair by ameliorating the glial microenvironment
PKC-dependent activation of human K2P18.1 K+ channels
Electrical conduction along endothelial cell tubes from mouse feed arteries: confounding actions of glycyrrhetinic acid derivatives
Inhibitory effects of dopamine on spinal synaptic transmission via dopamine D1-like receptors in neonatal rats