Analysis of variance: variably complex
Concordance of preclinical and clinical pharmacology and toxicology of monoclonal antibodies and fusion proteins: soluble targets
Concordance of preclinical and clinical pharmacology and toxicology of therapeutic monoclonal antibodies and fusion proteins: cell surface targets
Drug-like actions of autoantibodies against receptors of the autonomous nervous system and their impact on human heart function
A guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets
The use of animal models in diabetes research
The yin and yang of chemokine receptor activation
Pharmacological characterization of a small-molecule agonist for the chemokine receptor CXCR3
Small molecule chemokine mimetics suggest a molecular basis for the observation that CXCL10 and CXCL11 are allosteric ligands of CXCR3
Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist
Differential inhibition of tumour cell-induced platelet aggregation by the nicotinate aspirin prodrug (ST0702) and aspirin
Pharmacological activity of a Bv8 analogue modified in position 24
Dronedarone prevents microcirculatory abnormalities in the left ventricle during atrial tachypacing in pigs
The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH
Phospho-ibuprofen (MDC-917) incorporated in nanocarriers: anti-cancer activity in vitro and in vivo
Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat
Thiazolidinedione-dependent activation of sphingosine kinase 1 causes an anti-fibrotic effect in renal mesangial cells
Prostanoid EP1 receptors mediate up-regulation of the orphan nuclear receptor Nurr1 by cAMP-independent activation of protein kinase A, CREB and NF-κB
Activation of NK1 receptors in the locus coeruleus induces analgesia through noradrenergic-mediated descending inhibition in a rat model of neuropathic pain
Topical application of disodium isostearyl 2-O-L-ascorbyl phosphate, an amphiphilic ascorbic acid derivative, reduces neuropathic hyperalgesia in rats
Access of inhibitory neurosteroids to the NMDA receptor
The natural polyamines spermidine and spermine prevent bone loss through preferential disruption of osteoclastic activation in ovariectomized mice
A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease
Triptolide increases transcript and protein levels of survival motor neurons in human SMA fibroblasts and improves survival in SMA-like mice
Inflammatory muscle pain is dependent on the activation of kinin B1 and B2 receptors and intracellular kinase pathways
Adenosine-5′-triphosphate up-regulates proliferation of human cardiac fibroblasts
Caffeic acid phenethyl ester protects nigral dopaminergic neurons via dual mechanisms involving haem oxygenase-1 and brain-derived neurotrophic factor
Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic rats
Loss of multidrug and toxin extrusion 1 (MATE1) is associated with metformin-induced lactic acidosis
Corrigendum