Mechanistic analysis of the function of agonists and allosteric modulators: reconciling two-state and operational models
Calcium channel blockers and dementia
The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders
5-Chloroindole: a potent allosteric modulator of the 5-HT3 receptor
γ-Secretase inhibition promotes fibrotic effects of albumin in proximal tubular epithelial cells
Prolonged inhibition of 5-HT3 receptors by palonosetron results from surface receptor inhibition rather than inducing receptor internalization
Identification through high-throughput screening of 4'-methoxyflavone and 3',4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatos
Cardiovascular responses to retigabine in conscious rats – under normotensive and hypertensive conditions
Functional expression of KCNQ (Kv7) channels in guinea pig bladder smooth muscle and their contribution to spontaneous activity
Indoles mitigate the development of experimental autoimmune encephalomyelitis by induction of reciprocal differentiation of regulatory T cells and Th17 cells
Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue
Enhanced endothelin receptor type B-mediated vasodilation and underlying [Ca2+]i in mesenteric microvessels of pregnant rats
Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats
Activation of adenosine A2A receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation
Discovery of GW870086: a potent anti-inflammatory steroid with a unique pharmacological profile
Losartan protects liver against ischaemia/reperfusion injury through PPAR-γ activation and receptor for advanced glycation end-products down-regulation