From orphans to orexins: an arousing fifteen years
Discovery and development of orexin receptor antagonists as therapeutics for insomnia
Orexin/hypocretin receptor signalling: a functional perspective
Orexin/hypocretin receptor signalling cascades
The hypocretins/orexins: integrators of multiple physiological functions
Binding kinetics differentiates functional antagonism of orexin-2 receptor ligands
Molecular determinants of orexin receptor-arrestin-ubiquitin complex formation
PDGF and TGF-β promote tenascin-C expression in subepithelial myofibroblasts and contribute to intestinal mucosal protection in mice
Novel analogues of chlormethiazole are neuroprotective in four cellular models of neurodegeneration by a mechanism with variable dependence on GABAA receptor potentiation
The protein Ocular albinism 1 is the orphan GPCR GPR143 and mediates depressor and bradycardic responses to DOPA in the nucleus tractus solitarii
Structure–activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation
The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na+ channel, Nav1.5
Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block
Role of CXCR2 and TRPV1 in functional, inflammatory and behavioural changes in the rat model of cyclophosphamide-induced haemorrhagic cystitis
The cannabinoid CB2 receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis
Differential interactions of antiretroviral agents with LXR, ER and GR nuclear receptors: potential contributing factors to adverse events
Constitutive activation of AMPK α1 in vascular endothelium promotes high-fat diet-induced fatty liver injury: role of COX-2 induction
Detection of QTc interval prolongation using jacket telemetry in conscious non-human primates: comparison with implanted telemetry
Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1