Chemotherapy-induced changes in platelet function in early and advanced breast cancer
Local warming may augment the effect of antibiotic prophylaxis in breast surgery
Electrical field stimulation augments anastomotic healing in ischaemic bowel via local, not systemic mechanisms
Novel dendritic prodrugs of 5-aminolaevulinic acid for photodynamic therapy
Prognostic implication of plasma tissue factor (TF) and tissue factor pathway inhibitor (TFPI) in restenosis following percutaneous transluminal angioplasty (PTA)
Comparison of POSSUM, P-POSSUM and O-POSSUM in predicting mortality after oesophagogastric resections
Multipotent stem cells from adult blood - the future
Increased apoptosis and decreased proliferation of colorectal cancer cells caused by curcumin compared with NSAID
Characteristics of the in vitro inflammatory response in peripheral arterial disease (PAD)
BTW, a novel low-calcaemic vitamin D3 analogue selectively inhibits beta-catenin transactivation and tumourigenesis in vitro
A proteomic approach to the identification of pancreatic specific proteins
Genetic variation within the interleukin-6 (IL-6) gene determines IL-6 expression levels in human vascular cell models and in the carotid artery plaque
Dermal modulatory factor (DMF)
5T4 & CEA as potential targets for adoptive immunotherapy in the treatment of pancreatic cancer
Situational awareness skills may influence technical outcome in surgery
Nuclear MDM2 accumulation
Is it good to be bad?
Insulin-like growth factor binding protein-4 (IGFBP-4) gene therapy increases apoptosis of colorectal cancer by altering BAX/BCL-2 protein levels
Increased thermogenesis in an in vivo model of human sepsis is associated with changes in uncoupling protein gene expression in skeletal muscle
Reducing local recurrence of rectal cancer
The effect of obstetric trauma on the pudenda! nerve -a report on the development of an acute animal model to simulate the anatomical distortions associated with childbirth
Effects of fluid shear forces on human coronary artery smooth muscle cell gene expression and cytoskeletal organisation
Combined IFN-gamma-endostatin gene-therapy and radio-therapy attanuates primary breast tumour growth and lung metastases in a murine model via enhanced CTL and NK cell activation and attenuated tumour angiogenesis
Randomized controlled trial of sedation for colonoscopy
Abdominal aortic aneurysms secrete interleukin-6 - an in vivo study
The facilitative role of the extracellular matrix in the development of colorectal cancer liver metastases
Liver macrophages mediate cholangiocyte apoptosis and proinflammatory cytokine release during co-culture
Comparison of outcome between randomized and non-randomized patients in a clinical trial of asymptomatic inguinal hernias
Endothelin-1 stimulates desmoplasia in colorectal cancer
Methylene blue but not indigo carmine causes DNA damage to colon cells in vitro at concentrations used in clinical chromoendoscopy
A possible immunomodulatory role for gastrin?
The dose dependent effect of N-acetylcysteine on endothelial function in human saphenous vein graft
Automated quantitative analysis of immunohistochemistry linked to clinical outcome
Alpha-T-catenin, a novel gene involved in cell adhesion
Multiplex PCR-based approaches for determining the impact of genetic polymorphisms in peripheral arterial disease (PAD)
Recurrence rates after dynamic contrast enhanced-magnetic resonance image guided planning for breast conserving surgery following neoadjuvant chemotherapy for breast cancer
Axillary ultrasound can reduce the reoperation rate in node positive breast cancer
Hypertonic saline decreases post-operative adhesion formation
Portal tract mesenchyme provides a maturation signal to developing hepatoblasts
Transplantation of human haematopoetic stem cells to injured rat carotid arteries for vascular repair
Analysis of outcome in breast cancer
A prospective evaluation of CT features predictive of intra-abdominal hypertension and abdominal compartment syndrome in critically ill patients
Hsp90-binding agents improve outcome in kidney ischemia/reperfusion injury
The effect of mesenchymal stem cells on new bone formation in impaction grafting
Prothrombotic state in abdominal aortic aneurysm (AAA) patients
Increased expression of aromatase mRNA is correlated with poor clinical outcome in human breast cancer
Laparoscopic colonic resection in fast track patients does not enhance recovery after elective surgery
Hypoxia mediates invasion of breast cancer cells via increased expression of the chemokine receptor CXCR4
Objective assessment of surgical trainees for their error-economy movement ratio
The role of DCE-MR scan in planning surgery after neoadjuvant chemotherapy in patients treated for locally advanced breast cancer
Evaluation of vascular possum (V-POSSUM), ruptured aortic aneurysm possum (R-POSSUM) and glasgow aneurysm score (GAS) in predicting mortality for abdominal aortic aneurysmrepair (AAA)
Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-αB dependent activation of the urokinase plasminogen activator system
LDL-cholesterol is a major determinant of oxidative stress and endothelial dysfunction in patients with coronary artery disease
Expression of transcription factor, CREB-1 in human breast cancer and its correlation with prognosis
Differential kinetics of plasma CD105 and transforming growth factor-beta expression early in human acute pancreatitis
An immunohistochemical study of P16 expression in multistep thyroid tumorigenesis
Skeletal muscle oxygen metabolism; the effects of supervised exercise training for claudication
Quality of life following observation or operation in patients with an asymptomatic inguinal hernia
Angiogenesis and anaerobic glycolysis in colorectal cancers and liver metastases
Diagnosis of acute scrotal pain by hand held doppler; general surgeons experience
Increased expression of intrinsic markers of tissue hypoxia is observed following neo-adjuvant treatment of rectal cancer
Total cholesterol and fibrinogen underpin an abnormal clot structure in claudicants and their healthy first degree relatives
Constitutively active survival signals suppress mutagen-induced apoptosis during intestinal epithelial regeneration
Hypoxia-inducible factor (HIF)-1α, erythropoietin-receptor (Epo-R) and vascular endothelial growth factor (VEGF) expression in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence
Different pathways for the provision of CD4 T cell help for the generation of alloantibody and CD8 alloimmunity
Bi-directional upregulation of MMP-2 and MMP-9 following tumour-mesothelial contact – the role of CXCL12-CXCR4 interactions in peritoneal metastases
Role of endovenous laser treatment in the management of venous leg ulcers
Intravenous glycine improves bile flow and modulates bile composition in a in vivo warm liver ischaemia-reperfusion injury model
Evaluating the role of breast cancer angiogenesis and lymphangiogenesis on dynamic contrast-enhanced MRI
Systemic and organ specific inflammatory response following hepatic resection or ablation with radiofrequency ablation, cryotherapy and microwave tissue ablation
Topographical glycosaminoglycan variation in human articular cartilage
Vascular endothelial growth inhibitor represents an important target for therapeutic angiogenesis in the lower LIMB
Reduction of myointimal hyperplasia following arterial anastomosis by local injection of transforming growth factor β3
Steroid sulfatase mRNA expression is a significant prognostic marker in human breast cancer
Potent attenuation of local and metastatic tumour growth by taurolidine, in combination with radiation, in a murine melanoma tumour model
Human intestinal potassium channel function during metabolic stress
The effectiveness of specialist orthopaedic hospitals in england
Tamoxifen induces tumour cell apoptosis, decreases proliferation and blocks migration in anaplastic thyroid cancer (ATC)
The inflammatory infiltrate is a source of up-regulated interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP-1) within the abdominal aortic aneurysm wall
A novel painless method of ultrasonic debridement for chronic leg ulcers
Proteomic approach to discriminate between adriamycin sensitive and resistant breast cancer cells
A non-randomized controlled trial of endovenous laser therapy versus surgery in the treatment of varicose veins
Sex, systemic inflammation and survival in advanced pancreatic cancer
Targeted deletion of JNK-2 protects animals from hepatic ischaemia reperfusion injury
Dilatation of aortic necks following endovascular repair is greater in ruptured abdominal aneurysms than asymptomatic aneurysms
Functional characterisation of T-cell responses to telomerase immunotherapy in patients with advanced cancer
Peritoneal cytokines and drain fluid upregulate tumour cell UPAR expression and stimulate invasion
Human in vivo response to a cross-linked acellular collagen implant
Role of the mitochondrial apoptosis pathway in oxaliplatin and cisplatin – mediated toxicity in human HT29 colorectal cancer cells
Decreased substance P but not capsaicin receptor TRPV1 levels in rectal mucosa after successful sacral nerve stimulation for faecal incontinence
HMGB1 targeted immunotherapy provides unique protection against the local and systemic effects of acute pancreatitis
Impact of socio-economic deprivation on mortality rates after upper Gl cancer surgery
Glutamine preconditioning protects against tourniquet-induced local and distant organ injury
Variations in apoptosis gene expression by two different chemotherapeutic agents in gastrointestinal malignancy
Ischaemic preconditioning protects the intestinal microcirculation via expression of haem oxygenase-1 following ischaemia reperfusion injury of the intestine
Clinical evaluation of a new automated peripheral arterial disease assessment device (PODX) based on optical technique
Role of raman spectroscopy in the assesment of colorectal cancer with potential endoscopic application
Outcome of endovascular aneurysm repair in patients with difficult aortic necks
Molecular heterogeneity of distinct tumour foci taken from women with multifocal breast cancer
The addition of roll to fine wire localisation of impalpable breast lesions improves clearance and overall cosmesis
Coexpression of estrogen receptor alpha and beta is associated with reduced relapse-free survival in breast cancer
The systemic inflammatory response in patients undergoing coronary artery bypass grafting on- vs off-cardiopulmonary bypass
Cobalt particles induce inflammatory chemokine expression in primary human osteoblasts
Anterior anal sphincter repair
Protein profiling in the diagnosis of colorectal cancer
Near infrared raman spectroscopy – A new tool to help classify DCIS of the breast
Does core biopsy accurately diagnose breast carcinoma associated with radial scars and complex sclerosing lesions?
Gastric adenocarcinoma with distant metastasis
A study of the role of insulin like growth factor-1 (IGF-1) and rapamycin sensitive signalling in an androgen independent cancer cell line
Renal function following endovascular aortic aneurysm repair – Are supra-renal stent struts detrimental?
Percutaneous drainage of sterile acute fluid collections (AFC) in patients with severe acute pancreatitis
p53 and bcl-xl - Markers of axillary recurrence following axillary radiotherapy for primary breast cancer
The prevalence of abdominal aortic aneurysms in relatives in Northern Ireland
Is VEGF related to psychosocial factors in patients with colorectal cancer
Human single chain antibodies (SCFV), from a phage display library, against the NA1 domains of CEA
Specific identification of live probiotic organism bifidobacterium animalis subspecies lactis from faecal samples of surgical patients by fluorescent colony hybridisation assay
Elastic scattering spectroscopy – A rapid optical technique for detection of sentinel node metastases in breast cancer
Chronic pain following observation or operation in patients with an asymptomatic inguinal hernia
Fifteen year experience with the use of the angle bore socket in patients with an increased risk of dislocation following total hip replacement
Analysis of lumbar spinal motion in athletes during weight lifting
Serum albumin levels as a predictor of post-operative complications in patients undergoing upper gastrointestinal surgery
‘Surgent’ - A novel E-learning initiative for undergraduate surgical students