Effect of remote ischemic preconditioning on liver injury in patients undergoing hepatectomy for colorectal metastasis - a single center randomised controlled trial
Pregabalin prevents development of visceral hyperalgesia to oesophageal acid infusion in healthy volunteers
Lymphangiogenesis: novel involvement in abdominal aortic aneurysm (AAA)
Early liver ischaemic preconditioning reduces ischeamia reperfusion injury acting through nitric oxide synthase
Identification of potential therapeutic targets at the HER2/NEU amplicon
Insulin-like growth factor-1 receptor is upregulated in the leading edge of oesophageal adenocarcinoma and is associated with reduced survival
Heme arginate ameliorates hepatic ischaemia reperfusion injury through modification of macrophage phenotype
Xigris (human recombinant activated protein C) attenuates cerulein-induced experimental acute pancreatitis via regulation of NF-kB and apoptotic pathways.
The effect of the HIF-1 alpha C1772T heterozygous genotype on prostate cancer risk and HIF-1 alpha expression in prostate tissue
Differential Expression of Antimicrobial Peptides in the Female Urogenital Tract
Phenotypic analysis of the role of NK cells in the pathogenesis of abdominal aortic aneurysms
Self-endothelialisation potential of a novel nanocomposite material for development of cardiovascular implant: the role of progenitor stem cells
Human cancer cachexia - pathway analysis and identification of novel biomarkers in skeletal muscle
GR1+ macrophages are the primary producers of tnf following injury
Analysis of circulating monocyte subsets in critical limb ischaemia CLI)
Tissue engineering small bowel; an in-vitro study of epithelial cell growth on a new biodegradable nanocomposite polycaprolactone polymer scaffold
The role of the inhibitory Fc receptor in acute and chronic allograft rejection
A novel algorithm to predict HLA alloantigen immunogenicity based on the number and physiochemical properties of polymorphic amino acids
Defining the critical limits of renal warm ischaemia in a porcine model - preliminary report
Hypothermic machine perfusion versus static cold storage in a porcine kidney model of ischaemia reperfusion injury
Extracorporeal membranous oxygenation in a porcine non-heart beating liver model - a valuable tool for improving hepatocyte viability
Allospecific B cells can receive effective help from CD4 T cells that recognise an unrelated alloantigen
Leucocytes depletion improved renal function during reperfusion via reducing caspase-3 activity, apoptosis and IL-1B activation
Ureteric complications after kidney transplantation; risk factors and influence of donor type
Depot-specific determinants of ADMA generation by adipose tissue
Should surveillance endoscopy be the key focus to reduce mortality in Barrett's oesophagus?
A marked increase in activated pro-inflammatory T cells exists in the omentum of patients with gastrointestinal cancer
Complement C4A anaphylatoxin as a putative biomarker of response to neoadjuvant chemoradiation for oesophageal cancer
Improving the staging of oesophageal cancer: are changes to the N1 category needed?
MUC-1 and MUC-2 immunohistochemical and serological profile in Barrett's disease and oesophageal cancer
Does inflammation lead to activation of CDX2 and the metaplasia-dysplasia-carcinoma sequence progression in Barrett's oesophagus and oesophageal adenocarcinoma?
A potential new biomarker and treatment for oesophageal cancer
Morphology analyses of human carotid plaque in assessing fibrous cap rupture risk
Adaptive changes in skeletal muscle microvascular extracellular matrix in human critical limb ischaemia
Erythropoietin is angiogenic and tissue protective in human critical limb ischaemia
A novel approach to modelling abdominal aortic aneurysms
Activated satellite cell numbers and activity are increased in critically ischaemic human muscle
CXCL12 upregulated by hypoxia and stimulates cell proliferation via P44/42 and attenuates apoptosis via PI3/AKT pathways in angiogenesis
Can microvessel density and angiogenic growth factor expression distinguish differences in symptomatic versus asymptomatic carotid plaques?
Magnetic resonance T1-relaxation mapping quantifies venous thrombus organisation
Circulating micrornas in colorectal cancer
Bacterial dysbiosis in ileoanal pouches: an assessment of luminal flora in patients with ileoanal pouches using best culture techniques
Identification of colorectal cancer stem cells that self-renew, differentiate and drive tumour growth
The treatment of colorectal cancer metastasis with IGF-I receptor antagonists
Efficacy of the specific ETA receptor antagonist zibotentan (ZD4054) in cancer cells and fibroblasts from colorectal cancer
Analysis of microflora variance during treatment of pouchitis with VSL3 probiotic
Dietary agents in platinum resistance: potential for downstaging of colorectal liver metastases
Health related quality of life after open surgery with enhanced recovery protocols and laparoscopic colorectal surgery
CXCR4 and breast cancer, a role in metastases, a therapeutic target and a prognostic marker
AIB-1 and PEA-3; key mediators of breast cancer invasion
A study investigating the role of mammary adipose conditioned media on breast cancer: the influence of obesity and the metabolic syndrome
Development of a biocompatible fluorescent nanocrystal for sentinel lymph node biopsy
Microrna & predicted protein target expression in the circulation of breast cancer patients: novel biomarkers for breast cancer
The calcium binding protein S100B as a prognostic indicator in breast cancer
Deregulation of the oestrogen-finger protein EFP contributes to hormone-independent growth of breast tumours
Potential of circulating chemokines as serum tumour markers in breast cancer
Effect of angiotensin II and its receptor antagonists on human corpus cavernosal function
Does open surgical experience aid laparoscopic training?
A paradigm shift in modern surgical education
Surgical prophylaxis in familial adenomatous polyposis - do pre existing desmoids outside the abdominal cavity matter?
Self-appraisal in assessing operative performance in laparoscopic colorectal surgery
Meta-analysis of risk factors for desmoid development in familial adenomatous polyposis
The role of antibiotics in the primary treatment of acute non-perforated appendicitis
Randomised control trial of a structured curriculum to improve technical skills
A novel molecular pathway that drives tumorigenesis and invasion in glioblastoma
Tumour cell expression of protein C pathway receptors can mediate the interplay between coagulation proteases and malignancy
Signalling to S100Beta in malignant melanoma: the role of SRC-1 and HOXC11
Investigation of tumour-peritoneal interactions in the pathogenesis of peritoneal metastases using a novel ex vivo peritoneal model
Cyclin D1 expression influences overall survival in androgen independent prostate cancer
A bespoke 12-gene signature set is associated with pancreatic cancer metastatic capability
Pyruvate dehydrogenase kinase: an attractive target for metabolic anticancer therapy
Hypoxia depletes NAD+ which may promote development of colorectal liver metastases
The endothelin axis in drug sensitive and multidrug resistant bladder cancer cells
Reovirus activates human innate immune cell killing of colorectal cancer
Liver-intestinal cadherin (CDH17) is downregulated in colorectal cancer and associated with tumour progression
The accuracy of core needle biopsy in the diagnosis of soft tissue tumours
Long term glucocorticoid therapy leads to pancreatic acinar trans-differentiation into hepatocyte-like cells
The expression and co-localisation of trefoil factor family peptides and mucins in normal and diseased pancreas
Microrna mir-125a modulates post-resection intestinal apoptosis via downregulation of pro-survival Bcl2 family member MCL1
Contribution of proximal jejunum to intestinal glucose sensing and regulation of glucose absorption
Contribution of afferent and efferent vagal fibers to diet-induced obesity
Modulation of intestinal permeability by cannabinoids, cytokines and cannabinoid receptor antagonists in a novel in vitro model
Remote ischemic preconditioning reduces liver injury through modulating hepatic nitric oxide pathways
Nitric oxide and endothelial nitric oxide synthase activity are a prerequisite for the protective effects of hindlimb remote ischaemic preconditioning on liver ischaemia reperfusion injury
The effect of PECAM-1 polymorphism on neutrophil diapedesis
Assessment of disease severity in acute dextran sulphate sodium-induced colitis using simple objective measures
The role of neuropilin-1 expression in endothelial progenitor cell differentiation
A novel in vitro model of visceral pain using the human appendix
Distribution of lymphatics within dukes B colorectal adenocarcinomas using D240 immunostain
The mediators of warburg's effect in colorectal cancer: targets for future therapy
Inhibition of P38 MAPK sensitizes human colorectal cancer cells to 5-fluorouracil treatment
Prospective randomized double-blind placebo-controlled crossover study of sacral nerve stimulation in patients with severe rectal evacuatory dysfunction allied to rectal hyposensitivity
Survival after resection of the primary tumour in patients presenting with stage IV colorectal cancer
The water soluble statins, pravastatin and rosuvastatin, do not improve disease severity in dextran sulphate sodium-induced colitis in sprague-dawley rats
Interfering with IGF1 pathways to augment sensitivity of colon cancer cells to current chemotherapeutic agents
Faecal incontinence: are we losing our senses?
Global dna methylation is altered by neoadjuvant chemoradiotherapy in rectal cancer and may predict response to treatment
Modulation of the ubiquitin-proteasome pathway (UPP) sensitizes colonic carcinoma to apoptosis: the potential of proteasome inhibition in the treatment of colon carcinoma
The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a metaanalysis of randomised controlled trials
Autoantibody contributes to the development of allograft vasculopathy, but only in concert with conventional alloimmune responses
A novel pathway for recipient DC mediated alloresponses
Rapamycin toxicity in pancreatic beta cells is mediated via PKB
The role ot ltbetar signaling in the formation of ectopic lymphoid tissue within cardiac allografts
Cyclosporine versus tacrolimus for renal transplantation: 10 year follow up of a randomised controlled trial
Proton nuclear magnetic resonance spectroscopy of plasma in renal transplantation. Identification of biomarkers for delayed graft function and acute rejection
Proof of concept study: cardiac output increases after renal transplantation - a preliminary report
Mouse hindlimb remote ischaemic preconditioning reduces liver ischaemia reperfusion injury and improves hepatic microcirculatory blood flow
Initial experience of microdialysis as a method of monitoring inflammatory, ischaemic and immunological events following liver transplantation
Liver transplantation using donation after cardiac death donors: single-centre long-term outcome
Mesenchymal stem cells contribute to hepatogenesis in fetal liver
Tissue autofluorescence techniques and the early diagnosis of mouth cancer
Intra anal permacolTM for the treatment of passive faecal incontinence
Raised asymmetric dimethylarginine (ADMA) in ischaemic skeletal muscle
Acute traumatic coagulopathy is dependent upon injury load and shock
Does tailoring the teaching sessions of clinical teaching fellows according to the needs of different firms of 3-year medical students improve the feedback in a DGH?
Can we exclude appendicitis in patients with normal inflammatory markers?
Assessing generic & specific technical skills in lower gastro-intestinal endoscopies
Outcomes of the endovascular management of aortic arch aneurysm: implications for management of the left subclavian artery
HLA class I and class II expression on differentiated human embryonic stem cells and induced pluripotent stem cells
A novel antibacterial polymer: silver nanoparticle incorporated poss PCU
The effect of molecular weight of dextran sulphate sodium on the severity of acute dextran sulphate sodium-induced colitis in rats
An advanced computerised decision support system for breast cancer multidisciplinary meetings: results of an audit study
Oxidative stress in elective open versus laparoscopic colorectal surgery
Type of the first renal transplant rejection is a good indicator of graft survival
Perspectives towards surgery amongst UK medical students change during progress through medical school
Peri-operative N-acetylcysteine in major liver resection - does it influence outcome?
A postive B cell flow cytometry crossmatch significantly increases rejection rates in the first six months post renal transplantation
Radical surgery may not be necessary to reduce the local recurrence rate after abdominoperineal resection
Evaluation of the prognostic value of big endothelin-1 in patients undergoing potentially curative resection of colorectal cancer
Magic in practice: the nottingham experience
Radiation dose exposure for EVAR - is patient safety being compromised?
Colorectal subspecialisation and improved outcome following abdominoperineal resection for rectal adenocarcinoma
Tumour characteristics in breast cancer vary with ethnicity
Conjugation of quantum dots with RGD peptides: colon cancer cell targeting and toxicity assay
Influence of zinc and zinc chelator on HT-29 colorectal cell line
Pet scanning accurately predicts the extent of pre-operative colorectal hepatic metastatic disease
Longitudinal changes in gastro-oesophageal reflux from three months to six months post lung transplantation
Bilateral breast cancer: do synchronous and metachronous tumours represent different disease entities?
Localisation and quantitation of zinc and zinc transporters in colorectal liver metastases
Validity of pre-operative risk prediction methods for elective endovascular abdominal aortic aneurysm repair using a current multi-centre english dataset
The credit crunch time for the surgical societies
Poor attendance rates will impact upon the success of abdominal aortic aneurysm screening in northern ireland
Vacuum assisted closure therapy and septic open abdomen - is the combination safe?
A discrete-choice experiment to elicit patient preferences for the surgical management of oesophagogastic cancer
Patients with prostate cancer have a higher incidence of venous thromboembolic events following TURP than patients with clinical BPH
Impact of surgeon volume on outcomes of rectal cancer surgery
Neoadjuvant imatinib downsizes functionally irresectable rectal gists without raising overt resistant clones
Reperfusion as a marker of success of distal revascularisation (ramsor study)
A surgical ‘hospital at night’ programme facilitates early review of patients in the emergency department, but does not affect overall workload
Severity of oxidative stress may predict septic complications after elective colorectal surgery
Are surveillance renal transplant biopsies at 1 week useful?
Analgesia requirements in post-mastectomy microvascular breast reconstructions: total rib preservation versus rib sacrifice
Ultrasound guided intraglandular botox injections of major salivary glands for pharmacotherapy-resistant drooling in children
Assessing teaching performance of technical skills in surgery
How can the clinical teaching fellows tailor their teaching sessions according to the needs of different firms of 3-year medical students in a DGH to improve feedback?
Who do foundation year doctors choose as assessors?
Residual great saphenous vein is an important cause of recurrent varicose veins
Prognostic value of the trace element content in colorectal liver metastases
Antibacterial prophylaxis does not prevent mortality nor infection of pancreatic necrosis in acute pancreatitis
Carotid endarterectomy in the elderly: risks factors, intra-operative haemodynamics and short-term complications; a UK tertiary centre experience