Eicosapentaenoic acid (EPA) free fatty acid reduces polyp burden in familial adenomatous polyposis (FAP): Results of a randomised, placebo-controlled trial
Insulin-like growth factor 1 and its receptor correlates with obesity status in oesophageal adenocarcinoma tumours
Whole transcriptome profiling of peripheral blood in abdominal aortic aneurysm disease
Multi-analyte profiling and pathway analysis reveals a predominance of pro-inflammatory M1-type macrophage polarisation and evidence of IL17/TH17 signalling in symptomatic human carotid atherosclerosis
ATB-346, a hydrogen sulphide releasing derivative of naproxen, reduces ischaemia reperfusion injury (IRI) in a porcine model of donation-after-cardiac-death (DCD) kidney transplantation
Tumour PAI-1 overexpression correlates with visceral obesity and is an independent prognostic factor in oesophageal adenocarcinoma
O8 Bladder regeneration with decellularised xenografts in an animal model
The contribution of the RNA-binding protein RNPC1 to P21-mediated cell cycle arrest and radiation sensitivity in oesophageal cancer
A P-selectin polymophism is associated with the development of cancer cachexia: Results of a candidate gene association study
The CCL28 chemokine is differentially expressed in response to bile acid across the Barrett's oesophagus to adenocarcinoma sequence
A randomised controlled trial of omega-3 containing total parenteral nutrition. The impact on inflammatory response
O13 Creating a tissue engineered prosthesis for stress urinary incontinence and pelvic organ prolapse, which scaffold?
Activation of the wnt signalling pathway synergises with either PI3K or mapk activation to lead to urothelial cell carcinomas (UCC) with differing treatment requirements
The effect of sensory input from a cochlear implant on balance
Development and characterisation of a composite bioengineered nose for reconstruction post rhinectomy using a novel poss-nanocomposite polymer
Objective assessment of surgical trainees in selection for higher surgical training: The role of fundamental aptitude testing
Paradoxical enhancement of endothelial progenitor cells and endothelial regeneration in mice hemizygous for deletion of the type 1 insulin-like growth factor receptor
The effects of resistance training and neuromuscular electrical stimulation in knee osteoarthritis - a randomised control trial
Point of care diagnostics for the rapid identification of acute traumatic coagulopathy and prediction of massive trauma haemorrhage
Cardiac dysfunction after trauma: A real and present danger
Novel hybrid resuscitation in trauma improves coagulopathy and outcome
Rotem indices of platelet function in acute traumatic coagulopathy
Timing of mesenchymal stem cell transplantation into an area of acute myocardial infarction appears to be crucial for successful repair
Improving patient safety by preventing surgical infection - results of a two year initiative
Is the increase in cardiac-death organ donors in the uk contributing to a decline in brain-death donors?
Reduced levels of soluble urokinase receptor (supar) fragment DII-III predicts venous ulcers that fail to heal
Adipocytes are capable of presenting antigen in a MHC class II-dependent manner and activating Naïve CD4+ T cells
Cellular reprogramming by bacterial lipoprotein rescues ST2-deficient mice from lethal sepsis
Induction of gram-positive bacterial lipoprotein tolerance up-regulates genes that are involved in anti-microbial function while down-regulates genes responsible for proinflammatory response
Unravelling a novel role of myeloid-related proteins 8/14 (MRP8/14) in self tolerance and cross tolerance to gram negative and gram positive bacteria
Bowel biofeedback treatment in patients with multiple sclerosis: Psychological and disability factors, not physiological variables, predict success
Molecular profiling of colorectal cancer: Does it apply clinically?
Peristeen transanal irrigation in patients with multiple sclerosis
A randomised controlled trial comparing early home biofeedback physiotherapy with pelvic floor exercises following repair of third degree obstetric tears
Autophagy protects colon cancer cells against stress-induced death
The role of P38 MAPK pathway in human colon cancer cell resistance to 5-fluorouracil
Regional variation in urea transporter expression in human colon- a novel contribution to bacterial symbiosis?
Micrornas are differentially expressed in the circulation of colorectal cancer patients compared to healthy controls
Parametric survival analysis and predictive models for prophylactic surgery in familial adenomatous polyposis
Genome-wide methylation profiling of rectal tumours identifies novel markers of early stage disease
Disruption of microrna expression tips cellular regulation towards a carcinogenic phenotype
Patients with oesophageal carcinoma aged less than 50 years have improved survival
Nanoparticles for cancer treatment: Application of lectin (Glycoprotein) in the delivery of carbon nanotubes to the breast cancer cell
In-vitro charachteristics of desmoid tumour cells in familial adenomatous polyposis
Oncolytic virotherapy in an in vivo model of isolated limb perfusion for advanced extremity sarcoma
Huntingtin interacting protein 1 (HIP1) induces epithelial-to-mesenchymal transition (EMT) in prostate cancer cells
C-MYC induction of HES6 activates a distinct transcriptional network driving androgen insensitive prostate cancer
Thick melanoma - are we doing the right thing?
The RS10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine
Progesterone receptor status in breast cancer patients: Association with disease characteristics and patient survival
The inhibition of glycolysis using a pyruvate dehydrogenase kinase II inhibitor induces apoptosis and sensitises melanoma cells to temozolomide
Immunohistochemistry confirms downregulation of protein markers associated with resistance to radiotherapy
A potential role for iron and haem in breast cancer
Persistent elevation of Cystatin C following endovascular aneurysm repair (evar)
Negotiating tortuous iliac arteries in endovascular aneurysm repair
Identifying novel candidate genes in unstable carotid atherosclerotic plaques
VO2 peaks but anaerobic threshold is exhausted in the preoperative assessment of patients with abdominal aortic aneurysm
Discovery of plausible “candidate biomarkers of AAA” at protein level: A pilot study
Rates of spontaneous embolisation in acutely symptomatic patients with carotid artery disease
Identifying the risk of renal failure following elective AAA repair
Identification of differentially expressed proteins in hilar cholangiocarcinoma using a label free shotgun proteomic approach
The role of multislice computerised tomographic arterial portography in the detection of colorectal liver metastases, and the factors influencing perfusion defects
Upregulated Micro-RNA 21 targets PDCD4 inhibiting pancreatic cancer proliferation
Pathogenesis of chemotherapy associated liver injury prior to major hepatic resection
The role of a novel semi-synthetic flavonoid (MonoHer) in preventing monocrotaline induced sinusoidal obstruction syndrome in rats
The role of the bone marrow and notch signalling in the stromal microenvironment in cholangiocarcinoma
Tissue engineered trachea development using a novel nanocomposite material
The efficacy of antimicrobial wound dressings used in the management of military complex extremity injury: A pre-clinical randomized controlled trial
Evaluation of the biocompatibility of human grade chitosan derivative, human skin allograft and integra implant in rats
Trauma: Characterising the cytokine response to tissue damage
Enhanced haemocompatibility of POSS nanocomposite: A material of choice for cardiovascular application
HuR and its role in wound healing
The role of EHM2 in wound healing
Microrna-31 modulates tumour sensitivity to radiation in oesophageal cancer
A potential pathological role for omental CD8+ T cells in oesophageal adenocarcinoma
Pro-inflammatory and pro metastatic pathways are activated by obesity in barrett's metaplasia
Pre-treatment complement system serum protein levels predict response to neoadjuvant chemoradiation for oesophageal cancer
Omental adipose tissue increases oesophageal and colorectal tumour growth through a VEGF-mediated mechanism
Prognostic impact of P53 expression in oesophageal adenocarcinoma
Increased BMI does not adversely affect vascular function measured in vitro in obese patients
Excess visceral adiposity negatively influences post operative inflammatory response and risk of complications in patients undergoing gastrointestinal resection
SRC as a novel therapeutic target fot the treatment of triple negative breast cancer (TNBC)
Silencing of TLR4 increases tumour progression and lung metastasis in a murine model of breast cancer
Assessment of axillary lymph nodes using raman spectroscopyintraoperative use is possible
Trastuzumab treatment of endocrine dependent breast cancer cells results in upregulation of ERα
A differential intraoperative test for the detection of sentinel lymph node micro- and macro-metastases in breast Carcinoma. Results from the first UK centre routinely offering the service in clinical practice
Identifying new transcriptional targets for SRC-1 in breast cancer
Significant germline mutations predisposing to breast cancer among the indigenous western irish population
Evaluation of the contribution of genetic variance to chemotherapy response in breast cancer
Expression of genes related to neurotrophin signalling in breast cancer - in search of novel therapeutic techniques
TGF-β1 mediated stimulation of VEGF secretion by breast cancer cells
Development of immunohistochemical surrogates for prediction of breast cancer patient outcome via high-throughput antibody generation and validation using tissue microarray technology
Expression profiling of circulating miRNAs in breast cancer
Optimisation of cardiac preload and its effects on early graft function following renal transplantation using oesophageal doppler monitoring (ODM)
Experimental transplantation of decellularised intestinal scaffolds
Naked small interfering RNA (siRNA) of caspase-3 in preservation solution and autologous blood perfusate protects isolated ischaemic porcine kidneys
Hypothermic machine perfusion after static cold storage does not improve the preservation condition in an experimental porcine kidney model
Donor type does not influence the incidence of major urological complications after kidney transplantation
Pre-emptive immunosuppression using tacrolimus for living kidney transplantation
Primary human hepatocyte fate is modulated by intracellular reactive oxygen species generation and CD154 during hypoxia-reoxygenation injury
Donation after cardiac death (DCD) for liver transplantation: Identyfing the usable grafts
Positive luminex in cadaveric renal transplantation and its early predictability of graft function, rejection episodes
Longevity of the direct and indirect CD4 T cell alloimmune responses
B-cell rich nodular infiltrates in chronic allograft injury
The effects of urokinase on early graft function in live donor kidney transplantation
Blood volume displaced from an incompetent great saphenous vein during a standardised valsalva manoeuvre
Durability of a sutureless endovascular stent-graft based on nitinol stents bonded to a nanocomposite polymer
Immunohistochemical comparison of the nerve profile of vascular malformations: Implications for clinical management of venous malformation associated pain
Imaging intraplaque inflammation in carotid atherosclerosis with 11C-PK11195 PET/CT
Helix-B peptide of epo decreases ischaemia-induced apoptosis of skeletal myotubes
The use of computer aided diagnosis in risk assessment for abdominal aortic aneurysm rupture
Magnetic resonance T1 mapping predicts successful venous thrombolysis
Analysis of microvessels within carotid artery to determine plaque stability
Angiogenic monocytes mobilised in response to critical limb ischaemia are functionally impaired
A novel synthetic Ang-1 mimetic ligand for vascular protection and tissue engineering applications
An impact of institution-wide policy changes on two weeks target for carotid endarterectomy
Lamin A/C over- expression at regions exposed to high wall stress; A novel, mechano-sensitive pathway in abdominal aortic aneurysm (AAA) pathogenesis
Analysis of proteasomal subunit expression reveals RPT4 expression as a potential marker in colon cancer
Potential therapeutic impact of routine pre-operative staging with FDG-PET/CT in high and low risk rectal cancer
Characterisation of endothelin-1 binding sites in colorectal cancer and antagonistic action of the endothelin a receptor antagonist zibotentan(ZD4054)
Hypoxia inhibits colonic ion transport via activation of AMP kinase
The peri-operative role of the anti-neoplastic agent taurolidine in colon cancer: A prospective multicenter randomised clinical trial
Whole genome methylation analysis reveals a distinct pattern of methylation in colorectal cancer
Micrornas based blood assay for early detection of colorectal cancer
Does a preoperative cardiopulmonary exercise test identify a subgroup of patients who benefit from intraoperative goal directed therapy during elective colorectal surgery?
Endothelin-1 stimulated gene induction within colorectal fibroblasts and the effect of endothelin receptor antagonism on key genes
Effect of pelvic compression on nerve and blood supply to the anal canal in an animal model
AKT pathway as a potential therapeutic target for treating metastatic colorectal cancer
The effect of pre-operative adjuvant therapy on the body composition and cardiopulmonary status of patients with colorectal cancer awaiting resection
The effect of drugs commonly used for pyoderma gangrenosum on the efficiency of gene transfer to human keratinocytes
The liver-kidney ex-vivo autologus perfused porcine model for the study of islet autotransplantation in large animals
Application of proteomics to bile biomarker discovery in Cholangiocarcinoma
P-Possum score prediction of mortality in patients undergoing liver resection for colorectal metastases
“Recanalised umbilical vein: A method of measuring portal oxygenation”
The role of compression in ankle fracture
Bovine ureteric xenograft for difficult haemodialysis vascular access: Single centre experience over 4 years period
The use of nitroblue tetrazolium to detect bacterial viability as a method of assessing the efficacy of surgical skin preparations
HLA positivity by luminex crossmatch and its early effects in live donor renal transplantation
Assessment of the role of aptitude in the acquisition of advanced laparoscopic surgical skill sets: Results from a virtual-reality based laparoscopic colectomy training programme
A qualitative study of decision making (DM) in cancer care: a global perspective
Mutational analysis of colorectal cancers and dysplasia arising in patients with ulcerative colitis and comparison to their sporadic counterparts
The liver-kidney ex-vivo autologus perfused porcine model-a novel system for studying the renin-angiotensin system
Rectal irrigation: an effective option in the management of functional bowel disorders
Assessment of rectal afferent neuronal function using evoked potentials in patients with constipation and rectal hyposensation - A pilot study
Correlation analysis of initial aortic diameter, aneurysm volume and peak wall stress in abdominal aortic aneurysm (AAA) expansion
Role of NF-Kappa B signalling in neuroblastoma
Laser haemorrhoidectomy: An effective and ambulatory haemorrhoidectomy
The effects of psychological disturbances on pain and surgical outcome in patients requiring arthroscopic subacromial decompression
There is no role for intra-abdominal pressure monitoring following major elective colorectal surgery
Risk factors for complications following breast reduction
Long term outcome of uvulopalatopharyngoplasty (UVPPP) - a 10 year study
Temporary gastric neuromodulation for intractable nausea and vomiting
Characterising potential for pluripotency induction in human prostate tissue
Stem-cell regulatory protein Piwil2 enriches for known stem-cell and cancer stem-cell markers in prostate cancer cells
Synergistic effects of oncolytic reovirus and docetaxel chemotherapy in prostate cancer
The timing of prostate cancer diagnosis: Deprivation and psychosocial variables and their link with high risk disease
Predominance of CD8 T cell infiltration coincides with reciprocal reduction in regulatory T cells following prostate cryotherapy
The identification, internal and external validation of a biomarker panel to distinguish between Gleason 3 + 4 and 4 + 3 prostate cancer
Prostate specific antigen enhances the anti-microbial activity of SLPI and WFDC2
Loose versus stranded seeds for prostate brachytherapy - a systematic review and meta-analysis
An update on the prostate cancer stem cell model - CD133+ve stem cell enriched human prostate cells express active androgen receptor
Comparative meta-analysis of the human prostate stem cell transcriptome demonstrates that progenitor cells are the site of malignant transformation
The sun study-a biobank of sequential blood samples from patients with prostate cancer
Reversal of chemotherapy resistance in renal cell carcinoma side population using targeted agents as novel MDR modulators
The role of Src in renal cancer
The role of hypoxia-inducible MIR-210 in the biology and prognosis of clear cell kidney cancer
Resuts of kidney lesion experiments with haptic probe
Face, content and construct validity of a virtual reality simulator for robotic surgery
Evaluation of economic impact of robotics in urological surgery - a systematic review
Feasibility study for the development and implementation of centralised simulation training
Urinary MicroRNAs as a diagnostic biomarker in bladder cancer
Side population in human bladder cancer enriches for cancer stem cells that can be targeted by MAPK inhibition
Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer (visualised by micro CT)
Genome-wide copy number, FGFR3 and PIK3CA mutation analysis of multifocal non-muscle invasive bladder cancer
The optical properties of healthy versus cancerous urological tissue
Estrogen increases expression and secretion of the innate anti-microbial beta-defensin-2 in vaginal epithelium
Development of aseptically produced scaffolds for substitution urethroplasty
Microdialysis to monitor burn wound metabolism in the early post-burn period: Correlation with laser doppler imaging
Gram negative burn wound infection: Protagonists, trends and strategies
Polymer therapeutics for effective antimicrobial targeting in burn injury
Gastric perfusion: An outcome measure in burns resuscitation
Monocyte recruitment via the CX3CR1 receptor influences burn wound healing
Analysis of public attitudes towards the use of autologous and allogenic cells in tissue engineered products for burns
Topical negative pressure therapy: Does it accelerate neovascularisation within the dermal regeneration template, integra? A prospective histologica in-vivo study
The design and development of a new burns dressing
The physico-chemical properties of silver containing burn dressings
Facial reanimation utilising the ipsilateral masseter nerve to innervate a free gracilis transfer; our experience
Objective evidence for the use of Coleman fat transfer in scleroderma associated facial lipoatrophy
A robust approach to facial eye tracking experiments and their application to plastic surgery
Development of scaffold for auricular tissue engineering using a novel nanocomposite polymer
The role of disgust emotions in predicting post-operative wound care
Assessing the chondrogenic potential of a novel biometic nanocomposite polymer for tissue engineering a nose: The chondrocyte response to nanoscale
Development of a biocompatible fluorescent nanoparticle “quantum dot” for application in plastic and reconstructive surgery and an investigation into its cytotoxicity
Photothermal effect of heating carbon nanotubes using near infrared radiation: Applications in plastic surgery
Differentiation of adipose derived stem cells to Schwann cells on a novel nanocomposite polymer
Basic Burns Management e-learning tutorial: A new teaching tool