The in-vivo biocompatibility of a novel biodegradable fracture fixation device
Colorectal cancer stem cells and intestinal stem cells: The two faces of janus
Trends in mortality and incidence of abdominal aortic aneurysms in England and Wales
Global characterisation of the SRC-1 transciptome identifies disintegrin C as an ER-independent mediator of endocrine resistant breast cancer
Visceral obesity alters expression of inflammatory mediators in patients undergoing gastrointestinal resection
How do abdominal aortic aneurysms (AAA) grow?
Regulatory B cells induce long-term allograft survival in a mouse model of chronic rejection
Interleukin-15 potentiates CD8 and NK effector cell expansion and tumour killing in prostate cancer-peripheral blood mononuclear co-cultures
Blood based assay for early detection of colorectal adenoma and carcinoma
Disruption of eating patterns and intestinal glucose sensing in obesity-induced diabetes
Surgical stress increases muscle pyruvate dehydrogenase kinase-4 mRNA expression and impairs muscle pyruvate dehydrogenase complex activity, and may underlie postoperative muscle insulin resistance
The tumour suppressor gene, AIMP3 sensitises bladder cancer to chemo/radiotherapy in vitro and is a prognostic marker for overall survival in patients treated with radiotherapy for muscle invasive disease
Oesophageal adenocarcinoma targeted therapy: VEGF as a co-target with IGFIR inhibition
Normalization of the pro-thrombotic diathesis in patients with abdominal aortic aneurysm (AAA) following endovascular (EVAR) and open aneurysm repair (OAR)
Repigmentation of cutaneous scars in black and white skin: An observational study
Systemic inflammation and early breast cancer
Does hormone receptor status influence survival in HER2/neu positive breast cancer?
Gene silencing reveals a role for oestrogen finger protein (EFP) in tamoxifen resistance
Focal adhesion kinase plays a major role in the regulation of human DCIS stem cell activity
Cardiac glycosides as potential anti breast cancer agents
Oestrogen receptor negative/progesterone receptor positive (ER−/PR+) breast cancer phenotype: Incidence, management and outcomes in a symptomatic unit
MRI versus USS in the detection of axillary lymph node disease in patients with primary breast cancer
Circulating miR-497 as a novel minimally invasive biomarker for breast cancer
Optimising magnetic sentinel lymph node biopsy in breast cancer
The role of miRNAs in tamoxifen resistance in breast cancer
CXCR1/2 signalling regulates human breast cancer stem cell activity
Digital mammography in women AGED 35·40: Is there a role for opportunistic screening at a symptomatic breast clinic?
Bioluminescence mediated photodynamic therapy in breast cancer cell line
Cumulative effect of multiple low penetrance variants on breast cancer risk
Re-operations following laparoscopic adjustable gastric banding
Adenoviral mediated transcriptional targeting of colorectal cancer and effects on treatment resistant hypoxic cells
Detection of upper gastrointestinal pathologies with optical fibre probe fluorescence spectroscopy
Aerosolised intraperitoneal local anaesthetic (AILA) for laparoscopic surgery
Is the psychological impact of axillary hyperhidrosis altered by botox treatment?
Free-living physical activity as an outcome measure in patients with intermittent claudication
Role of VEGI/DR3 interactions in keratinocyte growth and migration: Implications to wound healing
The effects of cancer on outcomes following endovascular aneurysm repair
A meta-analysis of outcomes following use of somatostatin and its analogues for the management of enterocutaneous fistulas
Human gastric lipase augmentation of nasogastric tube aspirate pH tests
The presence of underlying malignancy is associated with improved outcome following faecal peritonitis: 7 year retrospective study
Inflammation is associated with epithelial apoptosis and decreased sulphation in the mucous gel layer of patients with ulcerative colitis
Strategies for inhibition of chemokine (CCL2) mediated monocyte migration in lethal reperfusion injury
Is antibiotic therapy as effective as appendicectomy in the treatment of uncomplicated acute appendicitis? - an updated metaanalysis
External validation of the BASIL survival prediction model in patients with peripheral arterial disease undergoing revascularisation and comparison with the FINNVASC and modified PREVENT scores
Critical limb ischaemia promotes an angiogenic drive that is mediated by the angiopoietin/Tie2 axis
Skeletal muscle damage in critical limb ischaemia (CLI) is mediated by toll-like receptors 2 and 6 activation
Magnetic resonance signal attenuation and image artefact testing of a nanocomposite polymer nitinol thoracic stent-graft
Statin therapy is associated with reduced risk of abdominal aortic aneurysm rupture
Pulsatile ante-grade great saphenous flow is associated with severe chronic superficial venous insufficency
A role for statins in promoting venous thrombus resolution
Contrast enhanced aortic ultrasonography - a laboratory phantom to determine the limitations of enhanced and unenhanced ultrasonography scanning for post-operative EVAR surveillance
A nanocomposite polymer based thoracic endoprosthesis to improve aortic compliance mismatch following endovascular repair
Application of mass spectrometric (MS) based proteomics coupled with artificial neural networks analysis for biomarker discovery of abdominal aortic aneurysm (AAA)
Tissue engineering small diameter bypass grafts: Decellularization and biocompatibility of porcine internal carotid arteries
5-year outcomes from a randomised clinical trial comparing 12 w versus 14 w endovenous laser ablation in the treatment of great saphenous varicose veins
Aortic stiffness as a predictor of abdominal aortic aneurysm (AAA) formation
Trends in statin therapy in vascular surgery patients and its effects on peri-operative and long term mortalities
Placebo controlled double blind randomised clinical trial of transversus abdominis plane block in live donor nephrectomy
Comparison of fresh frozen cadaver; high fidelity virtual reality simulator (lap mentor, simbionix) and box trainer as methods of training in laparoscopic incisional hernia repair
Emergency admission due to femoral hernia: A population based study using linked united kingdom primary and secondary care data
The validity and reliability of procedure based assessment in simulated vascular procedures
What is learnt by general surgical trainees in the operating theatre?
Optical fibre probe reflectance spectroscopy as a technique to diagnose lesions in the lower gastrointestinal tract
E-assessments - current perceptions in clinical practice
Comparison of fresh frozen cadavers and high fidelity virtual reality simulator as methods of laparoscopic training
Snail1: A marker of epithelial mesenchymal transition in gastro-oesophageal junction tumours
Relevance of tumour regression grade to oesophageal cancer staging post neoadjuvant chemoradiotherapy
Tissue metabolomics and oesophageal carcinogenesis
MAGIC regimen chemotherapy has a survival advantage compared to previous combinations treating gastro-oesophageal adenocarcinoma
The reliability of EUS in differentiating tumour stage in oesophageal carcinoma
Detection of upper gastrointestinal pathologies through quantification of optical coherence tomography signal attenuation using a linear model
Tumour regression grading correlates to survival in oesophago-gastric cancer. A report of current survival outcomes following neo-adjuvant chemotherapy
Can neoadjuvant chemoradiotherapy downstage node positive oesophageal cancer?
WAVE3 expression in human colorectal cancer
Development of a gemcitabine double emulsion for intratumoral therapy of pancreatic cancer
HIF-isoforms have divergent roles in the angiogenesis of colorectal cancer
RNAseq transcriptome analysis points to LINE1 chimeric transcripts as novel biomarkers for CRC
MTSS1 a negative regulator of migration and invasion of colorectal cancer cells
Investigating the potential use of LINE-1 chimeric transcripts as cancer biomarkers
Neuropilin-1: A predictor of early carcinogenesis in the colonic epithelium
The role of MiR-21 and Pdcd4 in colorectal cancer
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Islet transplant in an ex vivo porcine liver-kidney perfusion model
Normothermic kidney perfusion. The first clinical series
Naked small interfering RNA (siRNA) of caspase-3 was effective in preserving isolated porcine kidneys, but did not protect auto-transplanted kidneys
Withdrawn
The mitochondria-targeted antioxidant MitoQ ameliorates renal ischemia reperfusion injury in a murine model
Comparable outcomes for simultaneous pancreas kidney transplantation from controlled cardiac-death and brain-dead donors
Early urinary biomarkers of warm and cold ischaemic injury in an experimental kidney model
Prolonged cold ischaemia potentiates the mitochondrial damage that occurs during warm ischaemia in rat kidneys
A clinical audit & cost analysis of botulinum toxin therapy for chronic fissure-in-ano at a regional surgical unit
Toll-like receptor-4 signalling confers tumour survival via NOX generated reactive oxygen species in colon cancer
Anal acoustic reflectometry - a novel technique in the evaluation of male patients with faecal leakage
Prospective comparison of balloon expulsion, anorectal manometry and evacuation proctography for the diagnosis of evacuatory dysfunction
Hypoxia and lineage specification of colorectal cancer stem cells
Impact of hospital volume on outcomes of rectal cancer surgery: A systematic review and meta-analysis
Molecular insights into the impact of antibiotic and VSL#3® probiotic therapy on the microbiota of patients with pouchitis
The effect of parathyroid hormone on gene expression in an in-vitro model of the colorectal epithelium
Detection of lower gastrointestinal pathologies through quantification of optical coherence tomography signal attenuation using a linear model
Faecal butyrate levels have different effect on cancer and adenoma tissues: Suggestion of early beneficial role of butyrate during carcinogenesis
Identification of novel micrornas in development and progression of dysplasia and carcinoma in UC affected colon
Short chain fatty acids regulate the structure and function of K8, A major cytoskeleton protein in colonocytes
Does a pro-thrombotic environment contribute to the development of chemotherapy associated liver injury in patients with colorectal liver metastases?
The use of non-invasive MRI to quantify the effect of secretin on pancreatic blood flow and perfusion in healthy volunteers
Novel simple method for the isolation of pancreatic stellate cells
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Expression of the copper export transporter atpase 7B correlates with tissue specific injury in a murine model of colorectal liver metastases
Comparison of liver parenchymal ablation, tissue necrosis and lateral thermal spread using the harmonic scalpelTM, the ligasureTM, the cavitron ultrasonic surgical aspirator and the tissuelinkTM dissector
West Midlands regional audit on the management of gallstone pancreatitis-low adherence to the guidelines, but are they justified?
Outcomes after split and DCD liver transplantation: A comparison of marginal graft types
Post-operative computed tomography in pancreas transplantation
Biliary dysfunction in patients with sinusoidal obstruction syndrome
An in-silico study of the heparin interactome in pancreatic disease
Notch as a target for diagnosis and treatment of pancreatic cancer
Relationship between lean muscle mass and aerobic performance in colorectal cancer
Surgical resection relinquishes suppression of skeletal muscle turnover in cancer patients
A randomised controlled double-blind study on the effects of 1-liter intraoperative infusions over 1 hour of 4% succinylated gelatine (Gelofusine®) and 6% hydroxyethyl starch (Voluven®) on blood volume (NCT00868062)
The effect of dietary calcium supplementation and parathyroid hormone on gene expression in the rectal mucosa
The influence of ischaemia on the regenerative potential of skeletal muscle
Physical activity as an objective measure of functional recovery and quality of life following upper gastrointestinal cancer resection
Withdrawn
A randomised controlled trial comparing standard postoperative diet with low volume high calorie oral supplements in colorectal patients
The role of thromboxane synthase, prostacyclin synthase and the thromboxane receptor in the progression of oesophageal and their relationship to survival
Carnitine, pre-operative carbohydrate loading and post-operative insulin resistance: A potential mechanism
Deoxycholic acid drives mitochondrial instability during progression of Barrett's oesophagus to oesophageal adenocarcinoma
Skeletal muscle Akt in upper gastrointestinal cancer patients and its potential as a biomarker of cachexia
Encapsulation of angiogenic monocytes: A novel tool for cell therapy
A study of the test-retest reliability of pressure pain threshold in knee osteoarthritis
Withdrawn
Early removal of ureteric stents and its impact on reducing urinary infection in renal transplantation
Gene expression profiling and proteomic analysis of cartilage degradation in a mouse model of osteoarthritis
Tissue-protective effects of EPO and EPO-derivative in isolated human myoblasts
Characterisation of quiescent intestinal stem and cancer stem cells
Human aneurysmal vascular smooth muscle cell activation by oxidized phospholipid and inhibition by pyrazole-2
The hallucal metatarsosesamoid articulation - a three dimensional quantitive analysis
Expertise related disparity in prefrontal cortical excitation associated with intra-operative decision making
Endothelin-1 (ET-1) contributes to ischaemic skeletal muscle damage
Oncological & cosmetic re-intervention in immediate and delayed breast reconstruction
Gains iPhone App: Bringing breast cancer prognostication into the 21st century
Building the clinical evidence for day case breast surgery
Selection of patients for isotope directed enhanced axillary sampling (IDEAS) for screen detected early breast cancer
How are we managing malignant pleural effusions associated with breast cancer?
Early and delayed post-mastectomy breast reconstruction: A systematic review and meta-analysis
Management of trauma patients
The impact of using different gaming interfaces on virtual reality simulator scores
Cost and clinical implications of inappropriate pre-operative blood tests in elective surgery
Mentorship and role models in modern surgery: Prevalence and importance
The who surgical safety checklist, teamwork and workload in the operating theatre: A prospective, observational study
Preoperative oral carbohydrate loading in elective surgery: A meta-analysis
The association inguinal hernia with a single strenuous event
A trauma major haemorrhage protocol reduces waste and improves the delivery of blood component therapy
Angiotensin converting enzyme inhibitors effect on arterial stiffness: A meta-analysis of randomised controlled trials
Endovenous treatment for venous leg ulcers: Time for definitive evidence of clinical and cost-effectiveness
Patient influences and preferences for varicose vein procedures
Automated determination of the ankle brachial pressure index (ABPI) using the vicorder, validation versus manual measurement using hand-held doppler
Withdrawn
How should intervention for superficial venous insufficiency be commissioned?
Atypical smooth muscle cell morphology and function in abdominal aortic aneurysms
Pressure-related lateral displacement of anastomosed arteries and prosthetic grafts in an in vitro model: Implications for neointimal hyperplasia formation
Fenestrated endovascular grafts lead to deterioration in renal function
Delays in the patient pathway to urgent carotid endarterectomy for symptomatic internal carotid artery stenosis
Diagnosing acute diverticulitis - no standardised approach
Aetiology and outcome of severe acute intestinal failure
The introduction of a laparoscopic colorectal service and enhanced recovery program is associated with reduced length of stay, post-operative pain and complications
The role of neoadjuvant chemoradiotherapy and other factors in delayed wound healing following abdominoperineal excision of the rectum
Diffusion tensor imaging (DTI) of desmoid tumours in familial adenomatous polyposis: Initial experience
Can combined fluorine - 18 flurodeoxyglucose positron emission tomography (18f-FDG PET) and dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) predict behaviour of desmoid tumours in familial adenomatous polyposis (FAP) patients?
Porcine hepato-biliary and pancreas retrieval technique: Implications for organ preservation, physiological study and transplantation
Withdrawn
Audit on the management of acute pancreatitis - how good are we at following the guidelines?
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Managing oesophagectomies without routine critical care is safe and effective
Tumour cell invasion of lymphatics and vessels: Two important prognostic histological factors in the management of gastric tumours
Does running an established laparoscopic adjustable gastric banding (LAGB) bariatric service affect the acute surgical take?
Withdrawn
Implementation of a clerking proforma for tonsillar infection admissions
The use of robotics in otolaryngology-head and neck surgery
South West of England “Questionnaire Survey” on treatment practice for malignant melanoma (MM)
Ponseti technique achilles tenotomy: Can the feel of the tenotomy predict problems?
Minimising leg-length discrepancy following primary total hip arthroplasty: An intra-operative measurement technique
An audit of open partial nephrectomies
Natural history and outcome of patients with high risk non-muscle invasive bladder cancer (NMIBC) treated with bacille calmette guerin (BCG): A contemporary UK series
Development of a patient safety checklist for robot assisted urological surgery
The learning curve of skill acquisition on the SEP robot
Leiomyosarcoma of the scrotum - an exceptionally rare tumour. Case report and review of literature
Tissue diagnosis using a novel stiffness probe based on force and vision sensing: A feasibility study
The utility of transperineal template prostate biopsies in men deemed suitable for active surveillance for the management of prostate cancer
Introducing the productive operating theatre (TPOT) programme in urology theatre suites
Lineage tracking in situ : Where are the prostate stem cells? What are they doing?
The protein ps20 increases tumourigenic potential in prostate cancer epithelial cells
WFDC1/PS20 inhibits expansion of CD8-T cells and NK cells and effector cell mediated killing of prostate cancer cells in the prostate cancer microenvironment
Circulating MicroRNA signatures: A novel minimally invasive biomarker for prostate cancer
EMT biomarkers in prostate cancer progression
Induced pluripotent stem cell (iPSC) re-programming in the human prostate
Urinary ERG immunocytochemistry can identify prostate cancer patients prior to prostate biopsy
Withdrawn
The role of epithelial to mesenchymal transition (EMT) in iPS induction of human prostate
Retinoic acid receptor responder protein 2 (RARRES2) causes increased cell proliferation and migration in prostate cancer cells
Assessing the validity of the prostate cancer prevention trial prostate cancer risk calculator (PCPT-PCRC) in an Irish cohort
EphB3 and EphB4 receptor expression in prostate cancer - a future diagnostic and prognostic marker?
Uropathogen pattern and antibiotic resistance of catheter associated urinary tract infections in a UK university hospital
The anti-microbial peptide beta-defensin-2 protects the bladder against flagellated escherichia coli
Assessment of a variable stress rig to improve the properties of a tissue engineered prosthesis for use in stress urinary incontinence and pelvic organ prolapse
Assessment of urinary lactoferrin as a surrogate marker for urinary tract infection in patients with lower urniary tract symptoms
An innate immune response to motile e. coli is exhibited by both bladder and vaginal cells
Role of interstitial cells of cajal like cells in human neurogenic detrusor overactivity
Renal differentiation from adult spermatogonial stem cells
21-Activated kinases (PAKs) in urothelial cancer
Patient satisfaction with laser ablation of recurrent superficial tumours of the bladder via a flexible cystoscope under local anaesthesia
A pilot study of complement cascade activation as a marker for recovery following major abdominal surgery
The use of the internet and social software by plastic surgeons
Pre-tibial injuries in the older population: The impact on a plastic surgery department. Working towards day case management.
Can delayed microvascular breast reconstruction activate dormant breast cancer?
Botulinum toxin improves symptoms and hand function in Raynaud's syndrome secondary to scleroderma
Skin malignancies on the head and neck - whose specialty is it anyway?
Does patient height predict the intercostal space distance in women undergoing rib preserving internal mammary vessel exposure for free flap breast reconstruction?
A photogrammetric method for quantifying the effects of botulinum therapy for oral-ocular synkinesis: Validation of a new technique
Longevity of Becker-35 expandable implants in breast reconstruction: A 5 year review
Simultaneous endoscopic brow lift with upper lid blepharoplasty: Results from a single surgeons experience
Quantitative modelling of human epithelium in homeostasis and squamous cell carcinoma
Attitudes of medical students towards a career in plastic surgery
A prospective analysis of the role of incision biopsy in the management of cutaneous malignancy
The observer response to disfigurement: Designing facial eye tracking experiments
Repigmentation of cutaneous scars in black and white skin: An observational study
Perception and knowledge of appropriate first aid care in burn related injuries: Survey of english university students
Evaluation of high resolution digital thermal imaging in the assessment of burn depth
The effect of localised burn injury on skeletal muscle in a mouse model
Radio-controlled model vehicle fuel burns
Changing practice following development of guidelines for trace element supplementation in severe burns