Comparison of aberrant DNA methylation in rectal tissues before and after neoadjuvant chemoradiotherapy
Expression of gut homing molecules on perianal Crohn's fistulae
Host CD4 T cells are essential for diversification of donor induced humoral autoimmunity
Imaging parathyroid glands using confocal endomicroscopy: towards real-time intraoperative identification of parathryoid adenoma
Heterogeneity in indirect pathway CD4 T cell alloresponses
Gender- and regionally-specific decline in colonic neuromuscular activity with advanced age
A novel strategy to exploit metabolic dysregulation in oesophageal adenocarcinoma abolishes cancer cell proliferation
Survival benefit conferred by the androgen receptor is lost in aromatase inhibitor treated breast cancer
Fluorescent silica nanoparticles conjugated to anti-CEA antibodies allow tumour-specific imaging of colorectal cancer cells
The PXR as a drug target for the prevention of early graft loss following liver transplantation
Live imaging of human keratinocytes reveals two modes of cell proliferation
Endothelial colony forming cells (ECFC) and their role in tissue engineering and wound healing - migration, 3D tubule formation and expansion
Evaluating the roles of Wnt, P13k and MAPK pathways in prostate cancer
Up-regulation of the E2f family transcription factors via retinboblastima (RB) gene deletion results in high grade/muscle invasive bladder cancer in genetically engineered mouse models when combined with phosphatidylinositol 3-kinase (P13) pathway dysfunction
Endothelial dysfunction in intermittent claudication
The AVULS Trial - is simultaneous better?
A randomised control trial comparing endovenous laser ablation and conventional surgery for the treatment of small saphenous vein insufficiency; a 2-year follow-up
The risk of cerebral microembolisation and silent cerebral infarction with thoracic endovascular aortic repair
Post-transcriptional dysregulation of extracellular matrix modifying genes in patients with abdominal aortic aneurysms
Haemodynamic efficacy of the gekoTM electrical euromuscular stimulation device in claudicants
1H-nuclear magnetic resonance (NMR) spectrometric identification of biomarkers of atherosclerosis in the apolipoprotein-e knockout mouse
Factors influencing survival following elective abdominal aortic aneurysm repair
Aneurysm global epidemiology study: public health measures can further reduce abdominal aortic aneurysm mortality
Modelling outcomes following lower limb surgical revascularisation: the Vascular Society bypass outcome model (vs BOM)
Predictors of outcome in patients with peripheral arterial disease and diabetic foot ulceration
Prospective cohort study comparing concomitant ambulatory phlebectomies or foam sclerotherapy to varicose tributaries during EVLT: 2 year results
The impact of colorectal anastomotic leak and its treatment on cancer recurrence and survival following elective colorectal cancer resection
Prospective randomised mixed methods pilot trial of sacral and percutaneous tibial nerve stimulation for faecal incontinence
The morbidity of negative appendicectomy
Quality of anal evoked potential (AEP) recordings is reduced in patients with faecal incontinence (FI): evidence of central sensory pathway dysfunction?
Genetic and epigenetic factors in prediction of response to neoadjuvant chemoradiotherapy and clinical outcomes in rectal adenocarcinoma
Phenotypic analysis of primary colorectal cancer to inform the management of metastatic disease
DOK7 expression in colorectal cancer cells and association with clinical and prognostic outcome
Acute sacral nerve stimulation does not have a motor effect on the anorectum in an animal model
Apoptosis in rectal cancer biopsies following irradiation in a microfluidic device: a predictor of response?
Post-partum defecatory dysfunction: a complex problem involving co-existing faecal incontinence and constipation
Direct lines to colorectal cancer
Biosensor technology for early detection of anastomotic leak and intra-abdominal sepsis after gastrointestinal surgery
Prolonged allograft survival mediated by interleukin-10 expressing regulatory B cells requires B cell receptor ligation but not cognate T cell help
Stimulating macrophages to enhance liver regeneration
Targeting the BAFF/APRIL signalling axis for prevention of antibody-mediated allograft rejection
Impaired endothelium dependent relaxation - a proxy of viability for donation after circulatory death (DCD) kidneys
Cyclosporine a induced immediate vasoconstriction demonstrated during and impaired endothelium dependent relaxation demonstrated after reperfusion in a porcine donation after circulatory death (DCD) model
The effect of cold ischaemic time on cytokine and diabetes markers in pancreas transplantation
Human leukocyte antigen B-cell epitope tertiary structure and surface electrostatic potential reveal the molecular basis for alloantibody binding and epitope immunogenicity
Ex-vivo normothermic perfusion in marginal donor kidney transplantation
Depletion of murine intra-allograft B-lymphocytes inhibits renal chronic allograft damage
Viability assessment of discarded human kidneys using ex-vivo normothermic perfusion
The effect of formalising enhanced recovery after oesophagectomy
Faecal and plasma biomarkers combined with Bayesian prior risk modelling as a screening test for oesophago-gastric cancer
Attempted validation of the NUn score and inflammatory markers as predictors of oesophageal anastomotic leak
SIFT-MS analysis of exhaled breath for volatile organic profiling of oesophago-gastric cancer
The intial staging value of routine PET-CT In gastric cancer
Drug repurposing In oesophageal adenocarcinoma: new tricks For old dogs?
A decision tree analysis of selective endoscopic ultrasound in staging oesophageal cancer
The utility of restaging PET-CT In predicting progression to unresectable oesophageal cancer after neoadjuvant chemotherapy
The feasibility of applying metacognitive learning strategies to enhance simulation-based learning
The effect of divided attention on novices and experts in laparoscopic task performance
Metacognition In surgical skills learning
The effect of using deliberate practice to train interns on blood product prescibing - a prospective cohort analysis
Investigating the importance of variants at 12p11, 12q24 and 21q21 in breast cancer in the West of Ireland
The tissue factor pathway may promote breast cancer stem cell activity
Investigating the association between single nucleotide polymorphisms and indels in PCM1 (pericentriolar material) gene and breast cancer in the West of Ireland
14-3-3 proteins, tBID, Akt1 and FAKY397 may be predictive biomarkers of response to neoadjuvant chemotherapy in oestrogen receptor positive breast cancer as revealed by combined antibody microarray and 2d-Page/Maldi/Tof/Tof/Ms proteomics
Wide local excision defects of the breast - a treatment algorithm based on oncological resection patterns
Identifying novel breast cancer subtypes effect on clinical response to neoadjuvant chemotherapy
A new surgical protocol to reduce re-operation rates in breast conserving surgery
Altered glycosylation of IgA1 in breast cancer
Early graft loss after kidney transplantation: risk factors and consequences
A targeted glycoproteomic approach for the identification of a novel biomarker of metastatic breast cancer
The effect of eicospentaenoic acid nutritional supplementation on lean muscle mass and grip strength on patients undergoing curative resection of colorectal cancer - a double-blinded randomised control trial
Are we discarding transplantable donor pancreases? Correlation between donor demographics, surgical assessment and histopathology
Effect of radiotherapy on new generation of breast implants using silsesquioxane nanocomposites shell
Utility of histological assessment of donor kidney disease in predicting outcomes following deceased donor kidney transplantation
Mid-term survival outcomes for frail vascular surgical patients
Investigating peripheral haemodynamics during neuromuscular stimulation
The effect of interleukin 15 on an in vitro model of human keratinocyte cell migration in wound healing
Improved HLA-matching of first kidney transplants is required to avoid allosensitisation that precludes future re-transplantation
A pilot study to assess the effect of ramipril, on metalloproteinases and their inhibitors in claudicants
Perioperative prebiotics, probiotics or synbiotics for elective abdominal surgery in adults - a systematic review and meta-analysis of randomised controlled trials
The influence of breast cancer treatment on post-diagnosis weight gain. Results from the dietcomplyf study
Ischaemia reperfusion injury exacerbates chronic rejection in a mouse model of heart transplantation
NVR report on surgical outcomes and implications for minimum standards for “vascular centres” in the UK
Cadaveric organ donors are a promising source of viable haematopoietic stem cells for clinical use
A surgical rat model for investigating pharmacokinetic parameters of drug compounds
Are funnel plots an accurate way of assessing publication bias in meta-analyses of observational studies?
The effect of interleukin-17B on an in vitro model of human keratinocyte cell migration during wound healing
The reporting quality of randomized controlled trials in ophthalmic surgery in 2011: a systematic review
Cobalt alloy specific regulation of bone remodelling via HIF: a contributing cause of aseptic orthopaedic implant failure?
A nano-inspired multifunctional polymer platform for surgical applications
The effects of detergent sclerosants on white blood cells
A novel class of nanomedical antibiotics for surgical infection capable of localised activation and passive targeting
Do bacterial toxins drive the formation of nasal polyps in patients with chronic rhinosinusitis?
Glucose sensors and transporters in metabolic disease: analysis of tissue from obese diabetic and non-diabetic humans
The epo-derivative, ARA-290, attenuates ischaemia-induced skeletal muscle damage in CLI myoblasts in vitro and in a murine model of hindlimb ischaemia
Mesenteric vascular transit time, as assessed by contrast-enhanced ultrasound; its relationship to cardiac output and volume status
Assocation between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients
Acute endotoxaemia blunts nutrient mediated phosphorylation of muscle Akt/Mtor signalling and muscle protein synthesis in humans
Role of toll-like receptor 4 (TLR4) inhibition in ischaemia-induced systemic inflammatory response and skeletal muscle damage
Small bowel serosa, a novel source of proinflammatory cytokines in gut injury and inflammation
The LOX-1 scavenger receptor plays a dual role in atherosclerosis and regulates glucose metabolism
Intestinal nutrient sensing in the anti-diabetic effects of bariatric surgery
Peripheral neuropathy and the risk of cardiovascular events in diabetes mellitus
Cardiopulmonary exercise testing as a predictor of postoperative cardiac and pulmonary outcomes, early mortality and length of hospital stay in AAA repair patients
Toll-Like receptor 4 antagonism significantly improves fibroblast migration in simulated diabetic ischaemic conditions
Expression of hepatocyte growth factor-like/macrophage stimulating protein in human wound tissue and its biological functionality in human keratinocytes
The effect of varying doses of caffeine on laparoscopic skill performance in novices
A pilot study investigating the ability of advanced bipolar RF device to induce blood vessel haemostasis by activation of the coagulation pathway
Nutlin-3 is cytotoxic in TP53 WT liposarcoma and leiomyosarcoma in vitro and can act both synergistically and antagonistically with ionising radiation
The association of visceral adiposity with abdominal aortic aneurysm presence, size and ex-vivo fibrin clot structure
Anatomical examination of the elbow to determine if it is a potential source of vascularised tissue for reconstruction
Exosome-mediated active and selective secretion of MicroRNAs by breast cancer cells in vitro
Reduced glycosylation of SkBr3 breast cancer cells affects response to treatment
Enhanced mesenchymal stem cell immunomodulatory potency through intracellular budesonide microparticles
Sex differences in features of anorectal dysfunction: a consecutive study of 100 males and 100 females presenting for investigation of faecal incontinence
Glioma stem cells exploit host astrocytes to enhance tumour migratory and invasive capacity
Popliteal artery aneurysm growth rates in patients with multianeurysmal disease
Development and validation of condition-specific patient-reported outcome measures (PROMS) of quality of life, symptoms and treatment satisfaction for patients with aortic aneurysms
Decision making in symptomatic moderate carotid atherosclerosis: a survey of uk vascular surgeons and stroke physicians
Metabolic profiling in chronic venous ulceration of the lower limb - a new approach to an old problem?
Creating a predictive model of vein outcomes
Hospital based exercise programme improves preoperative aerobic capacity in abdominal aortic aneurysm patients
High susceptibility of human abdominal aortic aneurysm (AAA) vascular smooth muscle cells (VSMC) to apoptosis
Regional and systemic prothrombotic biomarkers in varicose vein patients and healthy controls
A randomised clinical trial comparing concomiant and sequential phlebectomy following endovenous laser ablation: 5 year outcome results
A systematic review of open repair versus fenestrated endovascular aneurysm repair of juxtarenal aneurysms
A UK perspective on independence and mobility following infra-inguinal lower limb bypass surgery for critical limb ischaemia
Sonothrombolysis - an in vitro and in-vivo study of thrombus dissolution using contrast enhanced ultrasound
The functional role of tertiary lymphoid organs in allografts
Hypermethylation of the BCRA1 promoter in blood DNA is associated with triple negative phenotype breast cancer
A randomised controlled trial to assess the mechanism by which a supervised exercise programme improves outcomes in patients with intermittent claudication
Unravelling the signalling pathways promoting fibrosis in dupuytren's disease reveals TNF as a therapeutic target
Towards restorative neurosurgery: interfacing neuronal networks with silicon-based microelectronics
Mitochondrial signalling pathways in the pathogenesis of acute necrotising pancreatitis
Use of a high-throughput polymer microarray to identify synthetic substrates that influence the behaviour of human adipose derived perivascular stem cells (PSC)
Cytochrome-C activity in human primary and metastatic colorectal tumours
Identification and validation of novel vascular endothelial therapeutic targets in colorectal cancer
Testing the efficacy of targeted theranostic liposomes in in-vitro cancer models
Dichloroacetate modulation of tumour metabolism to augment 5-aminolevulinic acid induced cancer fluorescence.
Development of a novel 3D matrix for in vitro tumour model studies
Discrimination of lymph node metastases using desorption electrospray ionisation-mass spectrometry imaging: a proof of concept study
Computer tomography defined body composition analysis and its relationship to the systemic inflammatory response in patients undergoing colorectal cancer surgery
Predictive validity of objective technical assessment within the National Training Programme for laparoscopic colorectal surgery
Deregulated stromal microrna-21 promotes metastatic progression in colorectal cancer
Under-recognised co-existence of constipation and faecal incontinence in the adult population: a large single-centre experience
Behavioural animal model of faecal continence
Educational level & colorectal cancer risk in developed countries: a systematic review & meta analysis
Time to dispense with mechanical bowel preparation? an observational study of colonic transit time following diverting loop ileostomy for low anterior resection
Histological and mechanical differences in the skin of patients with rectal prolapse
Defining the optimal conversion chemotherapy regimen for patients with inoperable liver only metastases from colorectal cancer - a systematic review and meta-analysis
Endogenous notch-driven tumorigenesis functions via notch3 to promote PI3k/AKT mediated cell survival in intrahepatic cholangiocarcinoma
Folfox induced sinusoidal obstruction syndrome (SOS) is a potentially reversible condition
Immune dysfunction and changes in intestinal morphology in patients with obstructive jaundice
The biological and clinical significance of different morphologic types of colorectal liver metastases
An investigation into the various morphological differences seen with the liver pathologies encountered within a cadaveric population
Treatment outcomes of foregut visceral arterial aneurysms (FVAA)
Assessment of the complication and operative outcome profile of synchronous liver and bowel surgery for colorectal cancer with liver-limited metastases
Outcomes of primary AV fistulae in elderly patients with end stage renal failure
The UK varicose vein story 1989-2010
Comparison of intermittent pneumatic compression and neuromuscular electrical stimulation using ultrasound and laser doppler fluximetry
Does laser wavelength have a clinical effect during endovenous laser treatment for superfical venous insufficiency? A prospective observational study comparing the 810 nm and 1470 nm endovenous laser wavelength
Alcohol intake and abdominal aortic aneurysm
The view of surgeons, general practitioners and patients on patient follow-up following varicose vein interventions in the UK
Safety of carotid surgery and intervention following thrombolysis in acute ischaemic stroke
Predicting cardiac events after endovascular aneurysm repair
The effects of prolonged warm ischaemic injury in an uncontrolled donation after circulatory death porcine kidney model
Systemic heparinisation in laparoscopic live donor nephrectomy
Patient and practitioner factors contribute to the failure of postoperative epidural analgesia
A qualitative content analysis of breast cancer narratives hosted through the medium of social media
PATI: Patient accessed tailored information
Patient reported outcome measures in septorhinoplasty surgery at a tertiary referral centre
Reducing unnecessary pre-operative testing in ENT surgery: clinical and financial implications
Nurse attendance at surgical ward rounds does not meet Royal College of Physicians' recommendations - a cause for concern or a sign of changing surgical practice?
Efficacy and safety of mesh in laparoscopic surgery for groin hernia: systematic review and meta-analysis
Multi-staged repair of contaminated primary and recurrent giant incisional herniae in the same hospital admission : a proposal for a new approach
A simple and an effective strategy for improving junior doctors' knowledge of intravenous fluid therapy
A survey to determine the use of smartphones amongst doctors working within surgical specialties
U1
Usp12 a novel AR co-regulator and PCa biomarker?
Regulation of the androgen receptor function by a metabolic kinase in prostate cancer
Interleukin-15 activates NK and CD8 T cells within the Prostate cancer microenvironment by expanding activatory NK cell receptors and attenuating inhibitory HLA ligands on tumour cells
Establishing a 3D primary tissue culture assay to explore self-renewal in murine adult prostate epithelial stem cells (PrSCs)
Spermatogonial stem cells: a route to preserving fertiltiy
AXL in bladder cancer: A marker of invasion, metastasis and promising therapeutic target
Methylation Status of HOXA9, SPAG6, ZIC1 and ZNF154 in Primary G3pT1 TCC Samples from a Bladder Cancer Prognosis Programme (BCPP) Cohort
Ciprofloxacin resistance and transrectal ultrasound (TRUS)-Guided biopsy sepsis: a prospective analysis
Urine biomarkers for prostate cancer
Can prenephroureterectomy ureteroscopy (PNU) reliably diagnose urothelial carcinoma in situ?
A Decision-analytic cost-effectiveness model to compare treatment options for radiation recurrent prostate cancer against androgen deprivation therapy
Comparison of radical treatment and mortality in patients with non-metastatic prostate cancer in England and USA
Is preoperative exercise to improve fitness before cystectomy feasible? Results from a randomised controlled study
Vasa nervorum in rat major pelvic ganglion are innervated by nitrergic nerve fibres
The detection and role of myofibroblasts in Peyronie's disease
Investigation of the role of myofibroblast differentiation in Peyronie's disease
Improving elastogenesis in a tissue engineered repair material for pelvic floor surgery
Interleukin-15 increases the lifespan and telomerase expression of CD8+ T, NK and NKT cells
The role of complement in renal ischaemia reperfusion injury
E. coli inhibits innate immunity to facilitate pyelonephritic infections
Oestrogen and the innate epithelial defences of the uro-genital tract
Uropathogenic Escherichia coli behaviour in different growth mediums and avoidance of the innate immune response
Autofluorescence signals for the detection of urinary bladder cancer
Investigating PARP-1 expression and activity in male and female, benign and malignant renal tissue
Circulating tumour DNA as a diagnostic aid in urological cancers
Identification of men with a genetic predisposition to prostate cancer: targeted screening in men at higher genetic risk and controls. The impact study.
Next generation sequencing of advanced non-castrate prostate cancer treated with docetaxel chemotherapy
Overcoming inherent variablity in prostate cancer TMA analysis using novel quantitative imaging for biomarker validation
Exploring the effect of the dietary bioactive sulforaphane on tricarboxylic acid (TCA) cycle intermediates in the human prostate
In vitro analysis of AMPK in human prostate cancer
Finding a niche. The location of human prostate stem cells
Are mentorship programmes in urology effective? A systematic review.
Face and content validation of the prostatic hyperplasia model and HOLEP simulator
Validation of the greenlight simulator and development of a training curriculum for greenlight laser prostatectomy
Urology MDTs : multi-disciplinary or multi-dysfunctional?
What is the role of expert mentoring in robotic surgical simulation? A randomised controlled trial.
Von Hippel Lindau renal cell carcinoma - surgical interventions, natural history and tumour growth rate
Biomedical markers of response to intravesical BCG treatment in high-risk non-muscle invasive bladder cancer
We report the outcomes after robotic-assisted laparoscopic radical prostatectomy for men with localised high-risk prostate cancer
Prostate gland lengths and iceball dimensions predict micturition functional outcome following salvage prostate cryotherapy in men with radiation recurrent prostate cancer
Computer aided image analysis and rapid prototyping molds using patient-specific MRI data for reliable comparison between imaging and histopathology of radical prostatectomy specimens
Does a negative MRI predict the absence of prostate cancer on transperineal mapping biopsies?
‘Stars the limit’- a unique bench model to aid vessel preparation skills
Effect of computer games and musical instruments on microsurgery
The ‘in-out-up-down’ training model for the development of dexterity and visuospatial skills in microsurgery: a validation study
A laboratory based microsurgical training programme to aid acquisition of microsurgical skills and help surgeons to objectify trainees level of proficiency
Antibiotic use in lower limb trauma - completing the audit cycle
Should thin melanomas be offered a sentinel node biopsy - a single institution analysis
‘All tied up’ a laboratory task in developing microsurgical skills
Squamous cell carcinoma excision in a tertiary referral centre - the importance of the deep excision margin
Management of open lower limb injuries - a regional experience
Being ‘Hot’ & ‘Cold’ with accident & emergency improves compliance to CQUIN targets
Demystifying coding
Revised estimates of mortality from the Birmingham Burn Centre, 2001-2010: a continuing analysis over 65 years
Albumin supplementation offers no benefit in burn patients
‘The haves and the have nots’- plastics teaching for undergraduates. an Anglo French comparison study
One-stage dynamic pelvic floor reconstruction following extra-levator laparoscopic abdomino perineal excision (ELAPE)
Taking a step in TBSA
The visor flap - a cultural solution