Resolution of (±)-trans-2-phenylcyclohexan-1-ol by lipases from Candida rugosa: effect of catalyst source and reaction conditions

    loading  Checking for direct PDF access through Ovid


Candida rugosa lipase resolved trans-2-phenylcyclohexan-1-ol. A commercial and a laboratory preparation were compared and better results were obtained with the latter (E >200). Both enzyme preparations were strongly dependent on the substrate concentration for their enantioselectivity. This effect could be due to the presence of an esterase activity unspecific for trans-2-phenylcyclohexan-1-ol. © Rapid Science Ltd. 1998

Related Topics

    loading  Loading Related Articles