Influence of RGD-containing oligopeptide-coated surface on bone formation in vitro and in vivo

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Abstract

New bone formation on an RGD-containing oligopeptide-coated surface in vitro and in vivo was investigated. The surface showed two-fold higher osteoblastic cell adhesion and differentiation in vitro, and revealed statistically significant in vivo bone formation compared with the control (P < 0.05).

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