Carotid artery intima-media thickness and stiffness index β changes in normal children: role of age, height and sex


    loading  Checking for direct PDF access through Ovid

Abstract

AimsThe need for early markers of atherosclerosis in paediatric ages has been emphasized recently. Few data are available on the behaviour of carotid intima-media thickness (cIMT) and arterial stiffness in normal children.MethodsWe studied prospectively 131 healthy children (78 boys), aged 3–16 years, by high-definition ultrasonography and echo-tracking technique in order to evaluate cIMT and stiffness index β.ResultsStiffness index β underwent a significant age-related increase (P < 0.001), and a positive relationship between cIMT and height was found in boys. In addition, stiffness index β and cIMT were not related to each other (P = 0.97).ConclusionThis study provides information about two markers of subclinical atherosclerosis, cIMT and carotid stiffness index β, in normal children aged 3–16 years. We found a significant age-related and height-related increase of stiffness index β in both sexes, whereas cIMT was positively related to height only in boys.

    loading  Loading Related Articles