SYNTHESIS OF 6-BROMOMETHYL-SUBSTITUTED DERIVATIVES OF PYRIDIN-2(1H)-ONES AND THEIR REACTION WITH NUCLEOPHILES

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Abstract

6-Bromomethyl-substituted derivatives of pyridin-2(1H)-ones were obtained by the bromination of 6-methyl-3,4-dihydropyridin-2(1H)-ones, and are the basis for the synthesis of thieno- and furo[3,4-b]pyridin-2(1H)-ones and also for obtaining new amino derivatives in the pyridin-2(1H)-one series.

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