Assessing usability of an electronic medical record is useful for organizations wishing to customize their electronic medical record and determine the impact on usability. The purpose of this article is to describe the development of a protocol to measure electronic medical record usability from a nursing perspective and to develop a scoring methodology. The Technical Evaluation, Testing, and Validation of the Usability of Electronic Health Records (NISTIR 7804), published by the National Institute of Standards and Technology, guided protocol development. Usability was determined by measuring effectiveness, efficiency, and satisfaction. Satisfaction was measured by the System Usability Scale, while effectiveness and efficiency were measured via performance testing by participants, who completed one of three scenarios. A protocol and scoring formula were developed and used to assess nursing usability, resulting in an overall “C” grade for the electronic medical record. Protocol implementation and the scoring/grading calculations can be replicated to assess electronic medical record usability. The three scenarios used in this protocol will be made available upon request from the primary author to promote the use of electronic medical record usability assessment. Using and expanding upon the government's recommended usability assessment guidelines, we were successful in measuring nursing electronic medical record usability and rating an electronic medical record.