Progression of Myocardial Necrosis During Reperfusion of Ischemic Myocardium

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Abstract

Background

The occurrence of myocyte necrosis during reperfusion of ischemic myocardium is controversial. This study measured myocardial 2-deoxyglucose uptake, correlated with histology, to determine whether loss of viability occurred during reperfusion of ischemic myocardium.

Conclusions

A large proportion of samples from infarcted myocardium are viable at the end of the ischemic period but lose viability during the first hours of reperfusion. (Circulation. 1998;97:795-804.)

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