[(: Can It Replace PET and Thallium SPECT for the Assessment of Myocardial Viability?18: Can It Replace PET and Thallium SPECT for the Assessment of Myocardial Viability?) F]Fluorodeoxyglucose Single Photon Emission Computed Tomography: Can It Replace PET and Thallium SPECT for the Assessment of Myocardial Viability?

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Abstract

Background

New high-energy collimators for single photon emission computed tomography (SPECT) cameras have made imaging of positron-emitting tracers, such as [(18) F]fluorodeoxyglucose (18) FDG), possible. We examined differences between SPECT and PET technologies and between18 FDG and thallium tracers to determine whether18 FDG SPECT could be adopted for assessment of myocardial viability.

Conclusions

Although18 FDG SPECT significantly increases the sensitivity for detection of viable myocardium in tissue declared nonviable by thallium (to 88% of the sensitivity achievable by PET), it will occasionally (27% of the time) result in falsely identifying as viable tissue that has been identified as nonviable by both PET and thallium. (Circulation. 1998;97:843-850.)

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