Relationship Between Left Ventricular Mass and Endothelium-Dependent Vasodilation in Never-Treated Hypertensive Patients

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Abstract

Background

Hypertensive patients are characterized by development of both left ventricular hypertrophy (LVH) and endothelial dysfunction.

Conclusions

Our data provide the first evidence that echocardiographic LVM in hypertensive patients is inversely related to FBF responses to the endothelium-dependent vasodilating agent ACh, but it is likely that both endothelium and LVM are damaged by hypertension. (Circulation. 1999;99:1991-1996.)

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