Infective Endocarditis in Hypertrophic Cardiomyopathy: Prevalence, Incidence, and Indications for Antibiotic Prophylaxis

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The literature on infective endocarditis in hypertrophic cardiomyopathy (HCM) is virtually confined to case reports. Consequently, the risk of endocarditis in HCM remains undefined.


Endocarditis in HCM is virtually confined to patients with outflow obstruction and is more common in those with both obstruction and atrial dilatation. These results indicate that antibiotic prophylaxis is required only in patients with obstructive HCM. (Circulation. 1999;99:2132-2137.)

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