From the The Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London, United Kingdom (H.B., D.J.H.); The National Institute of Health Research, Biomedical Research Centre, University College London Hospitals, United Kingdom (H.B., D.J.H.); Papworth Hospital NHS Trust, Cambridge, United Kingdom (H.B.); Barts Heart Centre, St Bartholomew’s Hospital, London, United Kingdom (D.J.H.); National Heart Research Institute Singapore, National Heart Centre, Singapore (D.J.H.); Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore (D.J.H.); and Yong Loo Lin School of Medicine, National University of Singapore (D.J.H.).