The Effectiveness of Several Current Soft Contact Lens Care Systems Against Aspergillus

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Fungal contamination of contact lenses is a common occurrence. In this study, we tested the effectiveness of currently used soft contact lens care systems against Aspergillus fumigatus.


We prepared and added 100 µL inoculums of 1 × 106 colony forming units/mL to each test solution. We exposed fungi to disinfectant for 4, 6, and 8 hours or to cleaning solution for 1 minute. We then diluted and plated the samples. After 48 hours, we counted the number of colony forming units.


We represented the cleaning agent results as a percentage of the number of colony forming units found in the control at the same exposure period: Quick CARE™ Starting Solution—0%, MiraFlow®—12%, Opti-Free® Daily Cleaner—41 %, and PureEyes™ Cleaner/Rinse—82%. We calculated the percent control for 4,6, and 8 hour exposures for each disinfecting solution: Opti-One®—197%, 163%, and 109%; Quick-CARE Finishing Solution—84.6%,55%, and 31%; ReNu®—97.4%,17%, and 4%; Complete®—10%, 1%, and 0.4%; PureEyes Disinfectant/Soaking Solution—0%, 0%, and 0%; and Hydrocare®—0%, 0%, and 0%.


This study of contact lens care systems provides a direct comparison of their effectiveness against the same strain of Aspergillus. The results allow practitioners to select the appropriate care system for each patient.

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