Genetic Diversity of Invasive Strains ofHaemophilus influenzaeType b before and after Introduction of the Conjugate Vaccine in Italy

    loading  Checking for direct PDF access through Ovid


We determined the genotypes of 95 invasive Haemophilus influenzae type b (Hib) strains collected before and after introduction of widespread Hib vaccination in Italy. No substantial change in genetic diversity was highlighted by pulsed-field gel electrophoresis. However, an upward temporal trend in proportion of strains possessing multiple copies of the capsulation b locus was detected (P = .03).

Related Topics

    loading  Loading Related Articles