Total situs inversus associated with the oculoauriculo-vertebral spectrum

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Abstract

A patient is reported with the association of the oculo-auriculo-vertebral spectrum and situs inversus. Conditions with overlapping features and previously reported conditions associated with the oculo-auriculo-vertebral spectrum are reviewed. These conditions, as well as the reported association of the oculo-auriculo-vertebral spectrum and situs inversus can probably be seen as a part of the mesodermal malformation spedtrum, due to an early abnormality in the development of the primitive streak or embryonic mesoderm.

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