Failure of Mebendazole in the Treatment of Humans with Trichinella spiralis Infection at the Stage of Encapsulating Larvae


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Abstract

Trichinella spiralis larvae infective for laboratory mice were collected from muscle biopsies performed at different times (from 1 day to 16 months) following the end of treatment, indicating the failure of mebendazole to kill Trichinella parasites when they are encapsulating in muscles.

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