Rapid Selection of Oseltamivirand Peramivir-Resistant Pandemic H1N1 Virus during Therapy in 2 Immunocompromised Hosts


    loading  Checking for direct PDF access through Ovid

Abstract

Pandemic 2009 H1N1 virus isolates containing the neuraminidase inhibitor resistance mutation H275Y have been reported. We describe rapid selection for the H275Y resistance mutation during therapy in 2 immunocompromised individuals at 9 and 14 days of therapy, as well as the first described case of clinically significant resistance to peramivir.

    loading  Loading Related Articles