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IN THIS ISSUE
Fat land: how Americans became the fattest people in the world
Do tumor-suppressive mechanisms contribute to organism aging by inducing stem cell senescence?
When cells get stressed: an integrative view of cellular senescence
VEGF: a critical player in neurodegeneration
Haldane, hot dogs, halitosis, and hypoxic vasodilation: the emerging biology of the nitrite anion
New viruses shake old paradigms
East meets West: an herbal tea finds a receptor
The relative roles of growth hormone and IGF-1 in controlling insulin sensitivity
Stat-3 is required for pulmonary homeostasis during hyperoxia
Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo
Cytotoxic T lymphocytes form an antigen-independent ring junction
Critical roles of TRAIL in hepatic cell death and hepatic inflammation
Triterpenoid electrophiles (avicins) activate the innate stress response by redox regulation of a gene battery
Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient
Estrogen stimulates microglia and brain recovery from hypoxia-ischemia in normoglycemic but not diabetic female mice
Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice
Nitrite in saliva increases gastric mucosal blood flow and mucus thickness
Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions
Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis
A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR