In this issue
Hopkins scientist tunes in to treat tuberculosis
Taking the direct route to make open access even easier
Fatal sequence
Murderous medicine
The L-type calcium channel in the heart
Pathogenesis of osteoporosis
Did dinosaurs have megakaryocytes? New ideas about platelets and their progenitors
Megakaryocyte biology and related disorders
The molecular mechanisms that control thrombopoiesis
The biogenesis of platelets from megakaryocyte proplatelets
Thrombus formation in vivo
Structure and function of the platelet integrin αIIbβ3
Platelet genomics and proteomics in human health and disease
Platelets in inflammation and atherogenesis
Minding the gaps to promote thrombus growth and stability
Is ghrelin a signal for the development of metabolic systems?
Expanding the immunotherapeutic potential of minor histocompatibility antigens
Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
Desperately seeking sugar
New ways in which GLP-1 can regulate glucose homeostasis
Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin
M-CSF mediates TNF-induced inflammatory osteolysis
Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays
Complete FcRn dependence for intravenous Ig therapy in autoimmune skin blistering diseases
Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia
Role of CCR5 in IFN-γ–induced and cigarette smoke–induced emphysema
Preferential migration of effector CD8+ T cells into the interstitium of the normal lung
Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes
Timp3 deficiency in insulin receptor–haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-α
A frameshift polymorphism in P2X5 elicits an allogeneic cytotoxic T lymphocyte response associated with remission of chronic myeloid leukemia
Control of homeostatic proliferation by regulatory T cells
The mitochondrial origin of postischemic arrhythmias
CD4+ T cell–independent DNA vaccination against opportunistic infections
Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors
Brain glucagon-like peptide–1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage
Mice lacking ghrelin receptors resist the development of diet-induced obesity
Absence of ghrelin protects against early-onset obesity
Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents
Pertussis toxin inhibits neutrophil recruitment to delay antibody-mediated clearance of Bordetella pertussis
Cross-reactive influenza virus–specific CD8+ T cells contribute to lymphoproliferation in Epstein-Barr virus–associated infectious mononucleosis
Identification of human urinary trefoil factor 1 as a novel calcium oxalate crystal growth inhibitor
Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells
GPR109A (PUMA-G/HM74A) mediates nicotinic acid–induced flushing