In this issue
Evolution, not revolution
A new JCI conflict-of-interest policy
Halfway there
Stem cells are on the House
The devil's doctor
Francis Crick
The fundamental basis of inflammatory bowel disease
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
Infectious disease, the innate immune response, and fibrosis
Models of liver fibrosis
The role of CXC chemokines in pulmonary fibrosis
Systemic sclerosis
ECM remodeling in hypertensive heart disease
Fibrosis and diseases of the eye
Mutations in coenzyme Q10 biosynthetic genes
CHIP-ping away at tau
Salt, sodium channels, and SGK1
HDL proteomics
Autoantibody selection and production in early human life
Scavenger receptors clear the air
Dependence of intestinal granuloma formation on unique myeloid DC-like cells
Shear stress–induced changes in atherosclerotic plaque composition are modulated by chemokines
Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8
Role for protease activity in visceral pain in irritable bowel syndrome
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy
Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition
Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin
High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2
Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation
Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics
Overexpression of Akt converts radial growth melanoma to vertical growth melanoma
PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR
Inhibition of protein kinase Cε prevents hepatic insulin resistance in nonalcoholic fatty liver disease
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL
Protection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/II
Prenyldiphosphate synthase, subunit 1 (PDSS1) and OH-benzoate polyprenyltransferase (COQ2) mutations in ubiquinone deficiency and oxidative phosphorylation disorders
Aldosterone-induced Sgk1 relieves Dot1a-Af9–mediated transcriptional repression of epithelial Na+ channel α
Impaired neutrophil activity and increased susceptibility to bacterial infection in mice lacking glucose-6-phosphatase–β
Role of a CUF1/CTR4 copper regulatory axis in the virulence of Cryptococcus neoformans
Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D–dependent mechanism
Hypotension, lipodystrophy, and insulin resistance in generalized PPARγ-deficient mice rescued from embryonic lethality
Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets
Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions
Immunopathogenesis and therapy of cutaneous T cell lymphoma