Tempus fugit
A conversation with Paul Greengard
Control of inflammation by integration of environmental cues by regulatory T cells
Coming of age
The role of mitochondria in aging
Causes, consequences, and reversal of immune system aging
Cellular senescence and the senescent secretory phenotype
The sirtuin family’s role in aging and age-associated pathologies
Rapalogs and mTOR inhibitors as anti-aging therapeutics
The role of aging upon β cell turnover
Telomeres and age-related disease
Insulin resistance in the vasculature
ROCKing pulmonary fibrosis
Creating new β cells
Virgin birth
Bathing the brain
Calcium flux and endothelial dysfunction during acute lung injury
IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality
Virus-induced hepatocellular carcinomas cause antigen-specific local tolerance
SHP-1 phosphatase activity counteracts increased T cell receptor affinity
Hypoxia-responsive miRNAs target argonaute 1 to promote angiogenesis
Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression
Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility
Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer
Smap1 deficiency perturbs receptor trafficking and predisposes mice to myelodysplasia
IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver
Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression
MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury
Transplanted progenitors generate functional enteric neurons in the postnatal colon
2-photon imaging of phagocyte-mediated T cell activation in the CNS
Endothelial ERK signaling controls lymphatic fate specification
Modified Foxp3 mRNA protects against asthma through an IL-10–dependent mechanism
Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling
Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis
Diabetes increases mortality after myocardial infarction by oxidizing CaMKII
Epigenomic plasticity enables human pancreatic α to β cell reprogramming
Parthenogenetic stem cells for tissue-engineered heart repair
Brain-wide pathway for waste clearance captured by contrast-enhanced MRI
PAR-1 contributes to the innate immune response during viral infection
Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis
p53 centrosomal localization diagnoses ataxia-telangiectasia homozygotes and heterozygotes
CXCL5 limits macrophage foam cell formation in atherosclerosis
TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer
HDAC4 controls histone methylation in response to elevated cardiac load
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors
Amelioration of arthritis through mobilization of peptide-specific CD8+ regulatory T cells
Adeno-associated virus capsid antigen presentation is dependent on endosomal escape
HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis