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IN THIS ISSUE
Translational Pharmacology: Harnessing Increased Specialization of Research Within the Basic Biological Sciences
HIGHLIGHTS
ASCPT NEWS
Pharmacovigilance, 2nd Edition
Effects of Inflammation on Pharmacokinetics/Pharmacodynamics: Increasing Recognition of Its Contribution to Variability in Response
Blunting of the Cardiovascular Effect of Aspirin by Ibuprofen: What Is the Evidence?
Response to “Pharmacodynamic Interaction Between Aspirin and Ibuprofen: A Plausible Mechanism of Aspirin Resistance”
Clinical Development of TLR Agonists as Adjuvants: “Post-alum Adjuvant” Candidates May Reach Beyond Their Intended Purpose
Response to “‘Postalum Adjuvants’ May Reach Beyond Their Intended Purpose: The Clinical Development of TLR Agonists”
The Polymorphisms Asn130Asp and Val174Ala in OATP1B1 and the CYP2C9 Allele *3 Independently Affect Torsemide Pharmacokinetics and Pharmacodynamics
Mice as Clinically Relevant Models for the Study of Cytochrome P450-dependent Metabolism
PK/PD Model of Indisulam and Capecitabine: Interaction Causes Excessive Myelosuppression
Pharmacokinetics, Pharmacodynamics, and Safety of a Prostaglandin D2 Receptor Antagonist
Effect of Semen Sampling Frequency on Seminal Antiretroviral Drug Concentration
Modeling and Simulation to Support Dose Selection and Clinical Development of SC-75416, a Selective COX-2 Inhibitor for the Treatment of Acute and Chronic Pain
Pharmacokinetics and Safety of Saquinavir/Ritonavir and Omeprazole in HIV-infected Subjects
New Adaptive Method for Phase I Trials in Oncology
Individualized Compared With Conventional Dosing of Enoxaparin
Lazarus's Gate: Challenges and Potential of Epigenetic Reprogramming of Somatic Cells
Inflammation and Altered Drug Clearance in Cancer: Transcriptional Repression of a Human CYP3A4 Transgene in Tumor-bearing Mice
Emerging Evidence of the Impact of Kidney Disease on Drug Metabolism and Transport
Mathematics for Understanding Disease
Development of Translational Pharmacokinetic-Pharmacodynamic Models
Integrating Family Medicine and Pharmacy to Advance Primary Care Therapeutics
Animal Studies in the Development of Medical Countermeasures
Clinical Pharmacology: Opportunities for Educating New Practitioners—An Australian Perspective