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Synopsis: This study was an uncontrolled, prospective trial in the setting of a university hospital intensive care unit designed to evaluate the usefulness of a systematic approach to acute respiratory distress syndrome (ARDS) management by use of a clinical algorithm. Patients with ARDS were treated according to a criteria-defined clinical algorithm that distinguished two groups of patients: (1) the advanced noninvasive treatment option group and (2) the same except for the use of extracorporeal membrane oxygenation (ECMO). A total of 122 patients were enrolled in the study, with an overall survival rate of 75%, with 89% survival in the noninvasive treatment group and 55% in the ECMO group, which are surprisingly much higher rates than previously reported.Source: Lewandowski K et al. High survival rate in 122 ARDS patients managed according to a clinical algorithm including extracorporeal membrane oxygenation.