Combination Therapy in the Treatment of Pulmonary Arterial Hypertension: Can That Dog Hunt?


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Abstract

Synopsis:The addition of inhaled iloprost in patients with pulmonary arterial hypertension with reduced exercise capacity already on bosentan monotherapy is safe and efficacious.Source:McLaughlin VV, Oudiz RJ, Frost A, et al. Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension. (STEP study: Safety and pilot efficacy Trial in combination with bosentan for Evaluation in Pulmonary arterial hypertension). Am J Respir Crit Care Med. 2006;174:1257–1263.

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