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Synopsis: There is no difference in incidence of ventilator-associated pneumonia in patients with early tracheostomy compared with late tracheostomy.Source: Terragni PP, Antonelli M, Fumagalli R, et al. Early versus late tracheotomy for prevention of pneumonia in mechanically ventilated adult intensive care units patients: a randomized controlled trial. JAMA. 2010;303:1483–1489.Also see the article in the current issue of Clinical Pulmonary Medicine by Makris and Nseir.