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Synopsis: In patients admitted to the hospital for community-acquired pneumonia, the use of prednisone for 7 days led to a shorter time to clinical stability, defined by vital sign stability for 24 hours, and an overall reduction in the length of hospital stay, with a higher incidence of hyperglycemia needing insulin, but without a difference in pneumonia-related complications at 30 days after randomization when compared with placebo.Source: Blum CA, Nigro N, Briel M, et al. Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomized, placebo-controlled trial. Lancet. 2015;385:1511–1518.