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Synopsis: The measurement of exhaled nitric oxide is becoming commonplace in the evaluation of patients with steroid-responsive asthma. This study showed that there might be utility to this test in the evaluation of patients without a known asthma diagnosis but who present with nonspecific respiratory symptoms.Source: Price DB et al. Fractional exhaled nitric oxide (FeNO) as a predictor of response to inhaled corticosteroids (ICS) in patients with nonspecific respiratory symptoms and insignificant bronchodilator reversibility: a randomized controlled trial. Lancet Respir Med. 6(1): 29–39.