Unsuspected strongyloidiasis in hospitalised elderly patients with and without eosinophilia

    loading  Checking for direct PDF access through Ovid

Abstract

ABSTRACT

The prevalence and associated factors of chronic uncomplicated strongyloidiasis were estimated among 200 consecutive elderly patients (aged ≥ 60 years) admitted to a general hospital in northern Italy. One-hundred patients had a peripheral eosinophil concentration ≥ 500 cells/μL (group A), and 100 were age- and gender-matched controls (group B). Measurements included serum IgG anti-Strongyloides antibody titre by an indirect immunofluorescence assay, combined with faecal culture for Strongyloides stercoralis. Anti-Strongyloides antibodies were detected in 28 patients (at high titre in 11 patients). Seropositivity was significantly more common among group A than among group B patients (OR 4.85). Strong seropositivity for anti-Strongyloides antibodies was associated with farm work (p < 0.001), but not with other patient characteristics or with signs and symptoms of strongyloidiasis. In conclusion, strongyloidiasis was relatively common among elderly in-patients; eosinophilia and a history of farm work were the most useful indications for this diagnosis.

Related Topics

    loading  Loading Related Articles