Myotonia Associated with Sarcoidosis: Marked Exacerbation with Pravastatin

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A 37-year-old man with sarcoidosis developed severe eleetrieal and clinical myotonia while taking pravastatin for hypercholesterolcmia. Myotonia associated with sarcoidosis is rare. Pravastatin is associated with myotonia in animals. This case suggests that sarcoidosis and pravastatin, two entities not frequently associated with myotonia, may interact in a synergistic manner to produce severe clinical myotonia in humans.

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