SYNTHESIS OF 17α-AMINO-5α-ANDROST-2-ENE FROM EPIANDROSTERONE

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Abstract

17α-Amino-5ga-androst-2-ene was synthesized from epiandrosterone via formation of the tosylate followed by nucleophilic substitution by azide and reduction with LiAlH4. The structures of the products were proved by NMR and IR spectroscopy and mass spectrometry.

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