ISOLATION OF LAPPACONITINE FROM ACONITUM SEPTENTRIONALE ROOTS BY ADSORPTION

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Abstract

Extracts of Aconitum septentrionale Koelle roots obtained using chloroform, isopropanol, and ethanol were purified using chloroform and basic γ-Al2O3. Ballast materials were selectively adsorbed by γ-Al2O3, increasing the mass fraction of lappaconitine in the extract. The ethanol extract was purified most. The degree of lappaconitine extraction by chloroform was unaffected by the presence of γ-Al2O3. However, the mass fraction in the extract and lappaconitine extraction from Aconitum septentrionale were increased more than twice.

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