Bone Marrow Uptake Complicating Radionuclide Venography in a Patient With Sickle Cell Anemia

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A 49-year-old black woman with hemoglobin SS sickle cell disease presented with right calf pain and swelling. She had a history of deep venous thrombophlebitis of the left calf. Because of the risks of iodinated contrast in patients with sickle cell disease, a radionuclide venogram was performed with Tc-99m labeled red blood cells. This revealed intense uptake in the bone marrow.

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