Cardiac Metastases of Neuroendocrine Tumors Treated With 177Lu DOTATATE Peptide Receptor Radionuclide Therapy or 131I-MIBG Therapy

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Abstract

Neuroendocrine tumors have a propensity to metastasize to the heart, although the reason for this remains unknown. A review of 251 neuroendocrine tumor patients treated with 177Lu DOTATATE peptide receptor radionuclide therapy or 131I-MIBG therapy at our institution since 2003 revealed 2 patients with cardiac metastases (incidence, 0.8%), one treated with 177Lu DOTATATE and one with 131I-MIBG. We present the imaging findings of these 2 patients, as well as their management and responses to therapy.

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