68Ga-PSMA Uptake by Dermatofibroma in a Patient With Prostate Cancer

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Prostate-specific membrane antigen (PSMA) is a typ. 2 transmembrane protein that is highly expressed in prostate cancer cells. 68Ga-PSMA PET/CT imaging is a modality used to determine the extent of prostate cancer. Various other neoplasias may also express PSMA, which appears as 68Ga-PSMA uptake in PET/CT imaging. A 71-year-old man with prostate cancer underwent 68Ga-PSMA PET/CT imaging for restaging after having an elevated prostate-specific antigen level. Subcutaneous lesions showing focal PSMA uptake were detected, one of which was excised. The histopathologic diagnosis was dermatofibroma.

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