Validity and Reliability of Turkish Version of the Functional Assessment of Cancer Therapy–Brain Questionnaire

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Background:Assessing the quality of life (QOL) of patients with brain tumors is ever more important, given increasing survivorship and the higher likelihood of developing potential morbidities associated with new therapies.Objective:The aim of this study was to adapt the Functional Assessment of Cancer Therapy–Brain (FACT-Br) Questionnaire for Turkish populations and test its validity and reliability.Methods:The questionnaire was first translated into Turkish and back-translated, adapting it to the Turkish culture. This Turkish version of the FACT-Br was administered to 500 patients. Confirmatory factor analysis was conducted to examine the scale’s construct validity. Test-retest and Cronbach’s α reliability coefficients were calculated to determine reliability of the total questionnaire and all subdimensions.Results:The questionnaire’s factor structure demonstrated good fit, implying that it could be applied to the Turkish population. Interclass correlation coefficients were between 0.93 and 0.99. The 5 subscales demonstrated good internal consistency, with Cronbach’s α ranging from .72 to .87. Overall, the reliability estimate for the total scale was 0.93. There was no difference between a 15-day test and retest coefficients for subscale and total scores, indicating stability.Conclusions:The Turkish version of the FACT-Br is a valid and reliable instrument that can be used to measure the QOL of patients with a brain tumor in Turkey.Implications for Practice:This assessment tool can be used in treatment evaluations and to evaluate other measures of QOL.

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