Endoscopic surgery, now widely used for multiple surgical procedures, is associated with many postoperative benefits. However, pathophysiological changes and side effects may occur intraoperatively. During CO2 pneumoperitoneum for laparoscopy, an increase in arterial pressure of CO2 and pneumothorax can occur. The increased intra-abdominal pressure will result in haemodynamic changes: a decrease in cardiac output owing to a fall in venous return, and an increase in systemic vascular resistance. The use of glycine-containing irrigation solutions for urological and gynaecological procedures can be responsible for the transurethral resection of prostate syndrome.